A d-uniform hypergraph H is a sum hypergraph iff there is a finite S ⊆ IN such that H is isomorphic to the hypergraph H+d (S) = (V, E), where V = S and E = {{v1, . . . , vd} : (i 6= j ⇒ vi 6= vj)∧ ∑d i=1 vi ∈ S}. For an arbitrary d-uniform hypergraph H the sum number σ = σ(H) is defined to be the minimum number of isolated vertices w1, . . . , wσ 6∈ V such that H ∪ {w1, . . . , wσ} is a sum hyp...

Vitamin D (VD) is a secosteroid hormone that is mainly synthesized in the skin upon exposure to UVB radiation. VD is widely known for its role in calcium metabolism; however, multiple endocrine, paracrine and autocrine functions of VD have been described, including a prominent role on carcinogenesis. In recent years, multiple associations between VD deficiency and different types of cancer have...

BACKGROUND Volumetric capnography dead-space measurements (physiologic dead-space-to-tidal-volume ratio [VD/VT] and alveolar VD/VT) are considered more accurate than the more readily available time-based capnography dead-space measurement (end-tidal alveolar dead-space fraction [AVDSF]). We sought to investigate the correlation between volumetric capnography and time-based capnography dead-spac...

All trans retinoic acid and vitamin D3 derivatives are well known for their antileukemic activity, while the precise mechanism of this effect remains to be clarified. Using human leukemic U937 and THP-1 promonocytic cell lines, we analyzed the effect of all-trans retinoic acid (RA) and/or 1,25-dihydroxyvitamin D3 (VD) on the generation of nitric oxide (NO), a potent antitumoral mediator. U937 c...

Although vitamin D (vD) deficiency is common in breastfed infants and their mothers during pregnancy and lactation, a standardized global comparison is lacking. We studied the prevalence and risk factors for vD deficiency using a standardized protocol in a cohort of breastfeeding mother-infant pairs, enrolled in the Global Exploration of Human Milk Study, designed to examine longitudinally the ...

OBJECTIVES To examine the clinical utility of 25-hydroxyvitamin D (25(OH)D) testing in achieving medium-term vitamin D (VD) sufficiency in a managed care population. METHODS Retrospective study of a continuously-enrolled patient population in a 3-year period between 2011 and 2013. Primary outcome was VD status at ∼1 year after 25(OH)D testing. Patient demographics, comorbidities, medications,...

BACKGROUND Since an originally anti-ulcer stable gastric pentadecapeptide BPC 157 (PL 14736) was shown to promote healing of injured striated muscle and smooth muscle in the gastrointestinal tract, we explored its therapeutic potentials for leak point pressure (LPP) recovery in rat stress urinary incontinence (SUI) after transabdominal urethrolysis (TU) and prolonged vaginal dilatation (VD). ...

N. Bingefors a, S. Bouvier ', S. Gidomski ', G . Hall d, T.S . Hogh e, P. Jalocha `, H. vd . Lippe J. Michel b , E. Nygârd f, M. Raymond d, A. Rudge g, R. Sachdeva d, P. Weilhammer g and K. Yoshioka g Uppsala University, Uppsala, Sweden h LEPS1,, Strasbourg, France ` Institute of Nuclear Physics, Cracow, Poland `t Blackett Laboratory, Imperial College, London, UK `" Norwegian Institute of Techn...

FOXP3-positive regulatory T (Treg) cells are a unique subset of T cells with immune regulatory properties. Treg cells can be induced from non-Treg CD4(+) T cells (induced Treg [iTreg] cells) by TCR triggering, IL-2, and TGF-β or retinoic acid. 1,25-Dihyroxyvitamin D(3) [1,25(OH)(2)VD(3)] affects the functions of immune cells including T cells. 1,25(OH)(2)VD(3) binds the nuclear VD receptor (VDR...