OBJECTIVES To describe short-term (up to 12 months) and long-term (up to 7 years) damage in patients with newly diagnosed antineutrophil-cytoplasm antibody-associated vasculitis (AAV). METHODS Data were combined from six European Vasculitis Study group trials (n=735). Long-term follow-up (LTFU) data available for patients from four trials (n=535). Damage accrued was quantified by the Vasculit...

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The aim of this study was to investigate the effect of commonly used botanicals on UDP-glucuronosyltransferase (UGT) 1A4, UGT1A6, and UGT1A9 activities in human liver microsomes. The extracts screened were black cohosh, cranberry, echinacea, garlic, ginkgo, ginseng, milk thistle, saw palmetto, and valerian in addition to the green tea catechin epigallocatechin gallate (EGCG). Formation of trifl...

Analysis of the emission caused by industrial facilities like chemical plants, refineries or other production areas is the first and most important step while calculating the noise pollution of the environment. Pipework with gas or fluid flows are often contributing relevant to the sound radiation of a complete facility. This radiation can be determined applying the methods described in technic...

The most important meteorological parameter affecting the human energy balance during sunny weather conditions is the mean radiant temperature T(mrt). It considers the uniform temperature of a surrounding surface giving off blackbody radiation, which results in the same energy gain of a human body given the prevailing radiation fluxes. This energy gain usually varies considerably in open space ...

Distributed File system was widely used as a cloud computing backend storage with high scalability, low cost, and reasonable sequential I/O performance. VDI I/O workload is mostly composed of small random I/O and distributed file system does not have enough performance for this I/O pattern. Compensating for this gap, we applied a cache using memory and SSD (Solid State Drive) to distributed fil...

Despite intensive efforts during the past 20 years, no generally accepted standard method exists to measure black carbon (BC) or elemental carbon (EC). Data on BC and EC concentrations are method specific and can differ widely (e.g. Schmid et al., 2001, ten Brink et al., 2004). In this study, a comprehensive set of methods (both optical and thermal) is compared. Measurements were performed unde...