In the present study, four new steroidal saponins, namely vernoniamyoside A-D (1-4), together with the two known steroidal saponins vernoamyoside D (5) and vernonioside B₂ (6) were isolated from the ethanol extract of leaves of the African medicinal plant Vernonia amygdalina Del. (Asteraceae). Their structures were demonstrated by spectral analyses along with 1D and 2D nuclear magnetic resonanc...

BACKGROUND Vernonia amygdalina, commonly called bitter-leaf, is widely consumed in many parts of Africa, and Nigeria, in particular. The leaf extract has been reported to have antimicrobial, anti-plasmodial, anti-helminthic, as well as prebiotic properties, but its immuno-modulatory effects have not been well-studied, neither have the prebiotics been identified. This study evaluated the immuno-...

Vernonia amygdalina is traditionally used to treat a variety of diseases including diarrhoea, fungal and bacterial infections, inflammation, cancer, diabetes, its squeezed juice can be applied on wounds. This study reviewed the phytochemistry, ethnopharmacological, pharmacological potentials V. amygdalina. Literature search relevant papers (1994-2021) were performed using ScienceDirect, Springe...

The leaves of Ocimum gratissimum and Vernonia amygdalina were analyzed for their chemical composition, minerals and vitamins. The results obtained from the analysis of the two plants were compared. The results revealed the presence of bioactive constituents comprising alkaloids (1.90 to 2.68 mg/100 g), tannins (0.04 to 0.07 mg/100g), saponins (0.06 to 2.94 mg/100 g), flavonoids (1.88 to 2.98 mg...