conclusions igm alone is not a marker for viral shedding in genital tract. molecular testing in conjunction of igg test should be evaluated as an option to determine hsv status, and applied for research on hsv genital infections records. methods two hundred and eight females were included in the study; igm antibodies against hsv1/2 were detected in serum samples; the real-time polymerase chain ...

background: salmonella enterica serovar typhi (s. typhi) the cause of the acute febrile disease typhoid fever is the major public health problem in developing countries. asymptomatic carriers are the main sources of typhoid. the aim of this study was to investigate methods for isolation and identification of s. typhi in asymptomatic carriers. materials and methods: two hundred stool samples wer...

hepatitis delta virus (hdv) infection results in more severe and even fulminant form of hepatitis b in co-infected cases. this study was designed to estimate the prevalence of anti-hdv positivity and the associated risk factors in patients with chronic hepatitis b virus infection in zahedan (iran). in this cross-sectional study a total of 440 consecutive patients with chronic hepatitis b virus ...

introduction : staphylococcus aureus colonization has been recognized as one of the most important risk factors for subsequent infections with this microorganism. in this study, we intended to identify all patients who were mrsa-positive upon admission and compare the prevalence of mrsa colonization on different days of study admitted in imam reza hospital in mashhad, iran. methods : this cross...

A model of long term viral persistence has been established by selecting a spontaneous mutant strain of influenza C/Ann Arbor/1/50 virus in a permanent carrier culture of MDCK cells. Infectivity and cell tropism are mainly determined by the multifunctional viral membrane glycoprotein (HEF). HEF analysis was aimed at identifying a putative correlation between sequence and function, i.e. receptor...

in this study, feasibility of upgrading and retrofitting municipal wastewater treatment plantswas investigated at laboratory scale using moving bed biofilm reactor (mbbr) process. for this purpose,an aerobic pilot was operated for nearly one year in different conditions, in which a moving bed carrier with aspecific biofilm surface area of 500 m2/m3 and a filling rate of 60% was utilized. system...

Restrictions in the diversity of an adaptive immune repertoire can facilitate viral persistence. Because a host afflicted with an immune deficiency is not likely to purge a persistent infection using endogenous mechanisms, it is important to explore adoptive therapies to supplement the host with a functional immune defense. In this study, we describe a virus carrier state that results from intr...

Persistence of even the stealthiest viruses can perturb immune function either to the benefit or detriment of the host. Lymphocytic choriomeningitis virus (LCMV) establishes lifelong, systemic persistence when introduced in utero or at birth. Despite a highly evolved host-pathogen relationship, LCMV cannot escape detection by the innate immune system, which results in chronic stimulation of the...

The use of carrier cells infected with oncolytic viruses in cancer gene therapy is an attractive method because it can overcome viral immunogenicity and induce tumor immunity and significant antitumor activity. To enable human clinical trials of this treatment, acute and chronic toxicity tests must first be performed to ensure safety. IAI.3B promoter, oncolytic adenovirus AdE3-IAI.3B introduced...

in this study, feasibility of upgrading and retrofitting municipal wastewater treatment plantswas investigated at laboratory scale using moving bed biofilm reactor (mbbr) process. for this purpose,an aerobic pilot was operated for nearly one year in different conditions, in which a moving bed carrier with aspecific biofilm surface area of 500 m2/m3 and a filling rate of 60% was utilized. system...