نتایج جستجو برای: visceral obesity

تعداد نتایج: 154418  

Journal: :British medical bulletin 1997
P G Kopelman L Albon

Obesity is characterised by alterations in metabolic function which result from a combination of increasing total body fatness and the regional distribution of adipose tissue. Abdominal visceral obesity is particularly associated with hyperinsulinaemia, increased portal vein free fatty acid concentration, hepatic gluconeogenesis, altered adrenocortical activity and androgen secretion and reduce...

2013
Hirofumi Nagao Susumu Kashine Hitoshi Nishizawa Takuya Okada Takekazu Kimura Ayumu Hirata Shiro Fukuda Junji Kozawa Norikazu Maeda Tetsuhiro Kitamura Tetsuyuki Yasuda Kohei Okita Toshiyuki Hibuse Mamiko Tsugawa Akihisa Imagawa Tohru Funahashi Iichiro Shimomura

BACKGROUND Although many Asian type 2 diabetic patients have been considered to be not obese and have low capacity of insulin secretion, the proportion of obese patients with visceral fat accumulation has increased in recent years. We found previously considerable number of Japanese non-obese subjects (body mass index (BMI) < 25 kg/m²) with visceral fat accumulation and multiple cardiovascular ...

2011
Tsutomu Shimada Tomoko Akase Mitsutaka Kosugi Masaki Aburada

"Boiogito" is a Kampo preparation which has been used since ancient times in patients with obesity of the "asthenic constitution" type, so-called "watery obesity", and its effect has been recognized clinically. In this study, we investigated the anti-obesity effect of Boiogito in the TSOD (Tsumura Suzuki Obese Diabetes) mouse, a model of spontaneous obese type II diabetes mellitus. Boiogito sho...

2014
Sue Kim Ji-Young Kim Duk-Chul Lee Hye-Sun Lee Ji-Won Lee Justin Y. Jeon

BACKGROUND Obesity, especially visceral obesity, is known to be an important correlate for cardiovascular disease and increased mortality. On the other hand, high cardiorespiratory fitness is suggested to be an effective contributor for reducing this risk. This study was conducted to determine the combined impact of cardiorespiratory fitness and visceral adiposity, otherwise known as fitness an...

Journal: :Journal of the American Society of Nephrology : JASN 2004
Brent E Wisse

The metabolic effects of obesity have made this highly prevalent disease one of the most common risk factors for diabetes, hypertension, and atherosclerosis, the leading causes of end-stage renal failure. However, obesity per se, as defined by body mass index, is less predictive of the development of these diseases than is the presence of a constellation of obesity-related abnormalities now kno...

Introduction: Omentin, an adipokine, with anti-inflammatory effects reduces insulin resistance, and can hence, play an important role in prevention of cardiovascular disease and diabetes. The present study aimed to investigate the association of plasma and dietary fatty acids with gene expression of omentin in visceral and subcutaneous adipose tissues. Materials and Methods: Visceral and subcut...

Journal: :Kidney & blood pressure research 2013
Sylwia Rotkegel Jerzy Chudek Urszula Spiechowicz-Zaton Rafal Ficek Marcin Adamczak Andrzej Wiecek

AIM/BACKGROUND Experimental and clinical studies revealed contradictory data concerning the influence of renin-angiotensin-aldosterone (RAA) system activation on visfatin release. The aim of the present study was the assessment of the effect of dietary sodium restriction with RAA system activation on visfatin level in hypertensive and normotensive patients with visceral obesity. METHODS The s...

2016
Yea Eun Kang Ji Min Kim Kyong Hye Joung Ju Hee Lee Bo Ram You Min Jeong Choi Min Jeong Ryu Young Bok Ko Min A Lee Junguee Lee Bon Jeong Ku Minho Shong Ki Hwan Lee Hyun Jin Kim

The roles of adipokines, proinflammatory cytokines, and adipose tissue macrophages in obesity-associated insulin resistance have been explored in both animal and human studies. However, our current understanding of obesity-associated insulin resistance relies on studies of artificial metabolic extremes. The purpose of this study was to explore the roles of adipokines, proinflammatory cytokines,...

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