AIM To investigate whether assigning young, healthy and motivated lay volunteer partners ("buddies") to adolescents with type 2 diabetes improves hemoglobin A1c (HbA1c). METHODS Adolescents with type 2 diabetes were randomized to partnering with a "buddy" or to conventional treatment. During the initial screening visit, which coincided with a routine outpatient diabetes clinic visit, patients...

PURPOSE Laxative-refractory opioid-induced constipation (OIC) is defined as OIC despite using 2 laxatives with a different mechanism of action (based on the Anatomical Therapeutic Chemical Classification System level 4 term [contact laxatives, osmotically acting laxatives, softeners/emollients, enemas, and others]). OIC has a significant impact on the treatment and quality of life of patients w...

BACKGROUND The purpose of this study was to assess changes in gastrointestinal symptom severity in patients with autoimmune disease who were switched from mycophenolate mofetil to enteric-coated mycophenolate sodium (EC-MPS). METHODS In this national, explorative, single-arm study, 111 patients were enrolled and switched to equimolar EC-MPS at baseline. The primary endpoint was change in the ...

We examine the correlation between the generosity of clinicians – as measured in a laboratory experiment – and the quality of care in their normal practices under three different intrinsic incentive schemes. Specifically, we observe clinicians in their normal work environment, when a peer observes them and six weeks after an encouragement visit from a peer. Clinicians who give at least half of ...

flowers, gay curtains hide the marks on the windowsills where the bars used to be. I climb the stairs and go along the endless corridors with the cell-like bedrooms on one side and the open ward on the other. More visitors today, wives are going home for Bank Holiday and husbands have brought suitcases... Grandma holds up a baby to his mother: 'Hasn't he grown! You'll be home soon, Jean shuffle...

By this time, the productive age was already overrun by millennials and gen z. Almost every day they do activities so tend to be monotonous saturated. People always need free time refresh their brains themselves from denseness of daily in order get a new spirit carry out future. Making paratourism is choice z today. doing visit, can enjoying tourist facilities natural scenery attraction Indones...