Obesity is one of the health problems in the developing and developed countries. Obesity subjects the individuals with metabolic and endocrine disorders. It is obvious that vitamin D deficiency or insufficiency may lead to secondary hyperparathyroidism. Thus, obesity increases the risk of vitamin D deficiency. Considering the high prevalence of vitamin D deficiency in children and adolescents w...

Vitamin E is found in high quantities in vegetable oils. Although vitamin E has multiple functions in humans and animals, its key function is protecting cells from oxidative damage. Since its discovery, several studies have demonstrated that vitamin E deficiency causes impaired fertility in humans and lab animals. However, the effects of vitamin E deficiency or of its supplementation on the fer...

OBJECTIVE To investigate the relationship between vitamin A deficiency (VAD), vitamin E deficiency (VED) and infectious diseases. PATIENTS AND METHODS We chose 684 cases of healthy children age 5 months-12 years from our hospital, measured their VA, VE from vein under the light proof condition with high-pressure liquid chromatography. Thereafter, the children who get the acute respiratory tra...

background vitamin d deficiency is believed to cause variety of abnormalities such as liver stiffness and fibrosis. it is also shown that vitamin d deficiency may result in chronic liver disease or liver cirrhosis. in this study, we aimed to systematically review the literature wherein the relationship between vitamin d deficiency and the severity of chronic liver disease or liver cirrhosis had...

BACKGROUND/OBJECTIVES Vitamin E is a fat-soluble vitamin and functions primarily as a lipid antioxidant. Inadequate vitamin E status may increase risk of several chronic diseases. Thus, the objectives of this study were to estimate intake and plasma concentration of each tocopherol and to evaluate vitamin E status of Korean adults. SUBJECTS/METHODS Three consecutive 24-h food recalls and fast...

Protein function is related to protein structure, and understanding disease-associated structural changes is critical both to understanding protein-mediated illness and to developing clinical therapies. We have developed a visual analytics tool called ContactWalker that uses molecular dynamics simulations to investigate the structural and physical differences between wild type and disease-assoc...

obesity is one of the health problems in the developing and developed countries. obesity subjects the individuals with metabolic and endocrine disorders. it is obvious that vitamin d deficiency or insufficiency may lead to secondary hyperparathyroidism. thus, obesity increases the risk of vitamin d deficiency. considering the high prevalence of vitamin d deficiency in children and adolescents w...

OBJECTIVE To determine the association between serum vitamin D level and left ventricular (LV) diastolic dysfunction. BACKGROUND Vitamin D deficiency has been shown in observational and prospective studies to be associated with cardiovascular diseases including coronary artery disease, LV hypertrophy and systolic heart failure. Even though diastolic LV dysfunction is an early manifestation of...

Serum vitamin E concentrations and vitamin E:cholesterol ratios in 31 patients with Friedreich's ataxia were not significantly different from values obtained from either disabled or ambulant control subjects. Although the clinical features of Friedreich's ataxia are similar to those associated with severe vitamin E deficiency, there are subtle but important clinical and neurophysiological diffe...

Vitamin B12 (cobalamin) is an essential coenzyme for nucleic acid synthesis. Animal protein is the major dietary source of vitamin B12. Deficiency of vitamin B12 leads to megaloblastic anemia, degeneration of the brain, spinal cord, peripheral nerves, and abnormalities of epithelial tissues. Two factors are necessary for the cure of megaloblastic anemia: one in food (extrinsic factor) and one i...