background: phytoestrogens are some plant compounds with estrogenic biological effects which are found in many nutritional sources as soybean, flaxseed and sesame. vitex agnus-castus, also called vitex, owns phytoestrogenic properties. studies have showed that phytoestrogens have different impacts on the gestation process and reproduction indices. the present study is aimed at investigating the...

Vitex agnus-castus has a long tradition as a herbal remedy and was used in ancient times not only as an anaphrodisiac and for preserving chastity but also against diverse disturbances of the female genital system. In actual clinical trials, the fruit Agni casti fructus was shown to relieve premenstrual syndrome (PMS) and especially breast swelling and pain, due to its dopaminergic effect. Altho...

OBJECTIVE Vitex agnus-castus (VAC) and its essential oil have been traditionally used to treat many conditions and symptoms such as premenstrual problems, mastalgia, inflammation, sexual dysfunction, and pain. In this study, the effects of essential oil extracted from Vitex agnus-castus (EOVAC) leaves were investigated in three behavioral models of nociception in adult male Wistar rats. MATER...

The efficacy of herbal extracts from the plants Vitex negundo and Acorus calamus against tick infestation in rat snakes (Ptyas mucosus) maintained under captivity was studied and compared to that of Ivermectin. A total of 6 rat snakes affected with heavy tick infestation were taken for the study. Investigation of ectoparasites in snakes under captivity showed abundance of Aponomma sp. ticks. Th...

CONTEXT The emergence and spread of Plasmodium falciparum-resistant parasites to nearly all available antimalarial drugs pose a threat to malaria control and necessitates the need to continue the search for new effective and affordable drugs. Ethnomedicine has been shown to be a potential source of antimalarial compounds or source of template for the synthesis of novel antimalarial molecules. ...

The beach vitex (Vitex rotundifolia L.), a member of the Lamiaceae family, is salt-tolerant, woody perennial common in coastal areas worldwide. Plant–fungal association was monitored shoreline forest area Wando Island Korea 2020, and leaf samples showing spot disease were collected. Eight fungal isolates recovered from on PDA identified based morphological characteristics multilocus molecular p...

Vitex genera is reputed for their medicinal properties. Of the 12 species reported to be present in Indian only 8 species are medicinally useful. Of these six species were colled and their pharmacognostic characters were studied and described.

Seven new labdane-type diterpenoids, vitextrifolins A-G (1-7), along with eight previously reported analogues, were isolated from the fruits of Vitex trifolia. The structures of 1-7 were elucidated by spectroscopic data interpretation. The isolates were evaluated for their cytotoxicity against four human cancer cell lines (A549, HCT116, HL-60, and ZR-75-30), but all were inactive (IC(50) < 5 μg...