Matrix-assisted laser desorption/ionization (MALDI), a soft ionization method, coupling with time-of-flight mass spectrometry (TOF MS) has become an indispensible tool for analyzing macromolecules, such as peptides, proteins, nucleic acids and polymers. However, the application of MALDI for the analysis of small molecules (<700 Da) has become the great challenge because of the interference from...

In this paper, we propose an interactive technique for constructing a 3D scene via sparse user inputs. We represent a 3D scene in the form of a Layered Depth Image (LDI) which is composed of a foreground layer and a background layer, and each layer has a corresponding texture and depth map. Given user-specified sparse depth inputs, depth maps are computed based on superpixels using interpolatio...

The use of silicon nanoparticles for laser desorption/ionization (LDI) is a new appealing matrix-less approach for the selective and sensitive mass spectrometry of small molecules in MALDI instruments. Chemically modified silicon nanoparticles (30nm) were previously found to require very low laser fluence in order to induce efficient LDI, which raised the question of internal energy deposition ...

• Average mass list and logarithm scaling is preferred for PCA to separate oils in scoring plot. Fig. 1: a) Zoom-in of LDI spectra of three different crude oil samples. b) Zoom-in of LDI spectra of three repetitive measurements showing the good reproducibility of the measurement. Fig. 2: Class distribution plot of different crude oils detected as radical cations and protonated species [H] by LD...

Electron trapping in a finite amplitude Langmuir wave (LW) leads to a frequency shift, ∆ωTP < 0 , and reduced Landau damping. These may lead to modulational instability. Its growth rate and damping threshold, due to escape of trapped electrons at rate ν, are calculated for the first time in the short wavelength regime. If the background plasma is in thermal equilibrium, it is shown that this tr...

Layered Depth Images (LDI) compactly represent multiview images and videos and have widespread usage in image-based rendering applications. In its typical use case scenario of representing a scanned environment, it has proven to be a less costly alternative than separate viewpoint encoding. However, higher quality laser scanner hardware and different user interaction paradigms have emerged, cre...

Evaluation of wetland ecological condition requires quantitative biological indices for measuring anthropogenic impairment. We implemented a modified floristic quality assessment index (FQAI) protocol for 75 isolated, depressional herbaceous wetland systems, exploring refinements of FQAI standard methods. Species encountered during sampling (n 5 397) were assigned coefficients of conservatism (...

BACKGROUND Stress questionnaires are included in many epidemiological cohort studies but the psychometric characteristics of these questionnaires are largely unknown. The aim of this study was to describe these characteristics for two short questionnaires measuring the lifetime and past year occurrence of stress: the List of Threatening Events (LTE) as a measure of acute stress and the Long-ter...

Biofunctionalized gold nanoparticles (AuNPs) enable innovative translational research and development in biomedicine. Biomolecules such as peptides, proteins, lipids, and carbohydrates can be assembled onto AuNPs to yield nanomaterials with unique properties for applications in imaging, photothermal therapy, vaccination strategies, and drug delivery. The characterization of functionalized AuNPs...

OBJECTIVE To evaluate the efficacy and safety of gemcitabine (GEM) at 30 min standard-dose infusion (30 min-SDI) compared with prolonged low-dose infusion (P-LDI) in patients with advanced non-small-cell lung cancer (NSCLC). METHODS Electronic databases including Pubmed, EMbase, Cochrane Library, CNKI, CBM, and VIP were searched using keywords "GEM", "P-LDI", and "NSCLC". Review Manager 5.3 w...