the objective of this study was to determine the prevalence and incidence of venous thromboembolism among critically ill medical surgical patients. in this cross sectional and retrospective study, we observed 243 patients who were first admitted at the intensive care unit. patients who were diagnosed with deep venous thrombosis or embolism either by clinical or paraclinical methods were enrolle...

BACKGROUND Low international normalized ratio (INR; <or=1.5) increases risk for thromboembolism. However, little is known about the epidemiology of low INR. METHODS AND RESULTS We prospectively collected data from 47 community-based clinics located throughout the United States from 2000 to 2002. We examined risk factors for low INR (<or=1.5), reasons given in the medical record for low INR, a...

BACKGROUND Venous thromboembolic events, either deep venous thrombosis or pulmonary embolism, are important complications in patients undergoing knee or hip arthroplasty. The purpose of this study was to evaluate the effectiveness of a mobile compression device (ActiveCare+S.F.T.) with or without aspirin compared with current pharmacological protocols for prophylaxis against venous thromboembol...

BACKGROUND Currently available antithrombotic prophylaxis is not perfectly reliable in elderly patients. The aim of this retrospective study was to evaluate the efficacy and safety of Compound Danshen Tablet (CDT) in preventing thromboembolism in multiple myeloma (MM) patients treated with thalidomide-based regimens. MATERIAL AND METHODS MM patients treated with thalidomide-based regimens were ...

patients and methods using current procedural terminology (cpt) codes for orthopaedic trauma procedures, we identified a prospective cohort of patients from the 2006 to 2013 acs-nsqip database. using wilcoxon-mann-whitney and chi-square tests where appropriate, patient demographics, comorbidities, and operative factors were compared between patients who developed a dvt within 30 days of surgery...

Venous thromboembolism produces chronic sequelae in the legs and occasional immediate mortality due to pulmonary embolism. Because it occurs in certain high risk situations (for example, after surgery) its prevention is a practical proposition. This has been attempted using many different approaches. Administration of low dose heparin with or without dihydroergotamine to enhance venous return h...

Oral anticoagulation is the therapeutic cornerstone in preventing thromboembolic risk in both atrial fibrillation (AF) and venous thromboembolism (VTE). After decades of the sole therapeutic oral anticoagulation option being warfarin, the introduction of non-vitamin K antagonist oral anticoagulants has heralded a new era. Edoxaban is the latest addition to these available for clinical use. Edox...

Protein S (PS) deficiency, an autosomal dominant hereditary thrombophilia, is more prevalent in East Asian populations than in Caucasians. PS-deficient patients have historically been administered a heparin product followed by warfarin for the treatment and secondary prevention of venous thromboembolism (VTE). However, warfarin can be ineffective or causes detrimental effects in rare cases. Whi...

pulmonary thromboembolism (pte) has a wide spectrum of presentations, and its c ardinal manifestations include chest pain, dyspnea, and syncope. syncope as an initial presentation of pte occurs in 10-14% of patients and is not restricted to massive ptes. it can also occur in the setting of non- massive cases probably due to a vasovagal mechanism or the occurrence of conduction disturbances in p...

More than 2.5 million Americans are chronically anticoagulated for indications including venous thromboembolism (VTE), mechanical heart valve(s), or atrial fibrillation (AF).1 Each year, 10% of these patients require temporary interruption of anticoagulation for an invasive procedure. Defining the most appropriate management strategy for these patients requires an assessment of the periprocedur...