Two cases of Wegener's granulomatosis occurred in two women aged 53 and 67 years. The clinical course in both was of rapid deterioration resulting from renal failure and leading to death. At necropsy both cases showed severe and disseminated necrotising granulomatosis in the lungs, kidneys, and spleen but with variable degrees of cardiac and systemic vasculitis. One patient, with appreciable ca...

Holger Fröhlich*, Jörg K. Wegner, Andreas Zell Center for Bioinformatics Tübingen (ZBIT), Sand 1, 72076 Tübingen, Germany {holger.froehlich,joerg.wegner,andreas.zell}@informatik.uni-tuebingen.de

Wegener's granulomatosis is an ANCA-associated small vessel vasculitis. Because histologically immune complex deposits are frequently lacking, the term pauci-immune has been introduced for this subgroup. We report a patient with fulminant, severe PR3-ANCA-positive Wegener's granulomatosis and multi-organ involvement (upper respiratory tract, lung, kidneys, skin and general symptoms), who showed...

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Necrotizing sarcoid granulomatosis (NSG) is a rare systemic disease characterized by confluent sarcoidlike granulomas with necrotic areas and a variable degree of vasculitis. First described by Liebow in 1973, NSG can be classified as a disease showing features of Wegener granulomatosis and sarcoidosis. The etiology and pathogenesis of NSG are so far unknown; it is considered to be unrelated to...

G. Wegner [12] gave a geometric characterization of all so–called Groemer packing of n ≥ 2 unit discs in E2 that are densest packings of n unit discs with respect to the convex hull of the discs. In this paper we provide a number theoretic characterization of all n satisfying that such a “Wegner packing” of n unit discs exists, and show that the proportion of these n is 23 24 among all natural ...

2. Connors W, Griffiths C, Patl J, Belletrutti PJ. Lymphomatoid granulomatosis associated with azathioprine therapy in Crohn disease. BMC Gastroenterol. 2014;14:127. 3. Ochi N, Yamane H, Yamagishi T, Monobe Y, Takigawa N. Metotrexate-induced lymphoproliferative disease: Epstein–Barr virus-associated lymphomatoid granulomatosis. J Clin Oncol. 2013;31:e348–50. 4. Chung JH, Wu C, Gilman MD, Palmer...