In many parts of the world, numerous outbreaks of pertussis have been described despite high vaccination coverage. In this article we report the epidemiological characteristics of pertussis in Brazil using a Surveillance Worksheet. Secondary data of pertussis case investigations reported from January 1999 to December 2008 recorded in the Information System for Notifiable Diseases (SINAN) and th...

BACKGROUND Appropriate antimicrobial therapy results in improved clinical outcomes in complicated intra-abdominal infections (cIAIs). Recent in vitro studies have reported increasing moxifloxacin resistance of Bacteroides species, thereby cautioning empiric use in infections with these organisms. METHODS This pooled analysis of 4 randomized clinical trials (2000-2010) evaluated the comparativ...

BACKGROUND The epidemiology of intussusception, including its incidence, can vary between different countries. The aim of this study was to describe the epidemiology of childhood intussusception in Japan using data from a nationwide inpatient database. METHODS We screened the database for eligible cases ≤ 18 years of age, who were coded with a discharge diagnosis of intussusception (Internati...

BACKGROUND Emerging interest is seen in the paradox of defibrillator shocks for ventricular tachyarrhythmia and increased mortality risk. Particularly in patients with dilated cardiomyopathy (DCM), the prognostic importance of shocks is unclear. The purpose of this study was to compare the outcome after shocks in patients with ischemic cardiomyopathy (ICM) or DCM and defibrillators (ICD) implan...

The Toxoplasma gondii rhoptry protein Rop2 was expressed in Escherichia coli as a fusion protein containing 44 kDa of the 55-kDa mature Rop2, supplied with six histidyl residues at the N-terminal end (Rop2196-561). Humoral response during Toxoplasma infection of humans was analyzed by immunoglobulin G (IgG), IgA, and IgM enzyme-linked immunosorbent assay with Rop2196-561 as the antigen substrat...

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Center for Disease Control and Prevention, Beijing, China 3 12 13 14 *To whom correspondence should be addressed: 15 Department of Virology II, National Institute of Infectious Diseases, 16 4-7-1 Gakuen, Musashimurayama-shi, Tokyo 208-0011, Japan 17 Phone:+81-42-561-0771; Fax:+81-42-561-4729 18 e-mail: [email protected] 19 20 Email addresses: 21 MA: [email protected] 22 HL: [email protected] 2...