نتایج جستجو برای: wrap53

تعداد نتایج: 72  

2005
Michael J. Kelley Kazuhiko Nakagawa Nicholas K. Conrad Jean LeRiche Nevin Murray Jin Soo Lee Jae Y. Ro Edward G. Shaw Margaret A. Tucker Bruce E. Johnson

We performed genetic analysis on 12 second primary non-small cell lung cancers in patients surviving small cell lung cancer to assess the potential contribution of smoking to the development of these tumors. Mutations of TP53 were found in three (25%) tumors, KRAS2 in three (25%) tumors, and CDKN2 in two (18%) tumors. Four (50%) mutations (one each in TPS3 and CDKN2 and two in KRAS2) were G:C t...

Journal: :Clinical chemistry 2010
Yiping Shen Bai-Lin Wu James F Gusella

Severe intellectual disability (ID), commonly referred to as mental retardation (MR), comprises a large collection of clinical conditions whose associated phenotypes include substantially below-average intelligence test scores and limited abilities in socially adaptive behaviors, such as communication, self-care, social interaction, and school functioning. ID/MR affects 1%–3% of the worldwide p...

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