نتایج جستجو برای: xr

تعداد نتایج: 1550  

Journal: :The international journal of neuropsychopharmacology 2011
Zuowei Wang David E Kemp Philip K Chan Yiru Fang Stephen J Ganocy Joseph R Calabrese Keming Gao

Quetiapine extended-release (quetiapine-XR) has been studied in patients with schizophrenia, bipolar mania, bipolar depression, major depressive disorder (MDD), and generalized anxiety disorder (GAD). The purpose of this study was to compare the tolerability and sensitivity of quetiapine-XR among these psychiatric conditions. The discontinuation due to adverse events (DAEs) and reported somnole...

Journal: :Clinical drug investigation 2017
Yumiko Matsuo Masafumi Okita James Ermer Toshihiro Wajima

BACKGROUND AND OBJECTIVE Guanfacine extended-release (guanfacine XR) could be a useful treatment option for children and adolescent patients with attention-deficit/hyperactivity disorder (ADHD). As an initial step in the development in Japan, the pharmacokinetics, safety and tolerability were assessed in healthy Japanese and non-Hispanic Caucasian adults. METHODS A Phase 1, double-blind, rand...

2014
Michel S Bourin Emanuel Severus Juan P Schronen Peter Gass Johan Szamosi Hans Eriksson Hongally Chandrashekar

Quetiapine extended release (XR) and lithium are treatments with proven efficacy in acute mania. This randomized study evaluated the efficacy and safety of lithium or placebo as add-on to quetiapine XR in adult patients with manic or mixed symptoms of bipolar I disorder. In this 6-week, double-blind study (Trial D144AC00003), adult patients with DSM-IV-TR-diagnosed bipolar I disorder (current e...

2014
Nobutake Yamamichi Chigaya Hirano Takeshi Shimamoto Chihiro Minatsuki Yu Takahashi Chiemi Nakayama Rie Matsuda Mitsuhiro Fujishiro Maki Konno-Shimizu Jun Kato Shinya Kodashima Satoshi Ono Keiko Niimi Satoshi Mochizuki Yosuke Tsuji Yoshiki Sakaguchi Itsuko Asada-Hirayama Chihiro Takeuchi Seiichi Yakabi Hikaru Kakimoto Ryoichi Wada Toru Mitsushima Masao Ichinose Kazuhiko Koike

BACKGROUND Double-contrast upper gastrointestinal barium X-ray radiography (UGI-XR) is one of the most widely conducted gastric cancer screening methods. It has been executed to find gastric cancer, but has not been usually executed to detect premalignant atrophic mucosa of stomach. To understand the meaning of UGI-XR-based atrophic gastritis, we analyzed its association with several causative ...

Journal: :Epilepsy & Behavior 2015
Scott T. Brittain James W. Wheless

BACKGROUND Once-daily extended-release (XR) antiepileptic drugs (AEDs) offer potential adherence and tolerability advantages over their BID immediate-release (IR) counterparts. However, patients with epilepsy will inevitably be at least occasionally nonadherent with a prescribed dosing regimen, regardless of formulation. Although perturbations in plasma concentrations due to dosing irregulariti...

2001
Maria Carmen Leonardi Julio Cesar Sampaio do Prado Leite

Resumen. Extreme Requirements (XR) es una propuesta que procura dar mayor calidad a la conducción de proyectos en Extreme Programming (XP), una de las metodologías más usadas dentro de las metodologías conocidas como ágiles cuyos elementos claves son: poca documentación, simplicidad, análisis como una actividad constante, diseño evolutivo, integraciones y testeo diarios. XR define una estrategi...

1998
M. FRANCO Wei Y. Loh J. M. RUIZ

In this paper, we show a unified approach to the problem of characterizing general distribution functions based on the conditional expectation between adjacent order statistics, ξ(x) = E(h(Xr,n) | Xr+1,n = x) or ξ(x) = E(h(Xr+1,n) | Xr,n = x), where h is a real, continuous and strictly monotonic function. We have the explicit expression of the distribution function F from the above order mean f...

Journal: :The American journal on addictions 2016
Daniel P Notzon John J Mariani Martina Pavlicova Andrew Glass Amy L Mahony Daniel J Brooks John Grabowski Frances R Levin

BACKGROUND AND OBJECTIVES The prevalence of ADHD is greater in substance use disorders than the general population, and ADHD and substance use disorders share neurobiological features such as dysregulation of reward circuitry. We tested the hypothesis that stimulants would decrease marijuana use in a randomized controlled trial of extended release mixed amphetamine salts (MAS-XR) for treatment ...

Journal: :Current medical research and opinion 2005
M van Baardewijk P M J Vis T R Einarson

PURPOSE To determine the cost effectiveness of duloxetine, a new serotonin norepinephrine reuptake inhibitor, when compared with venlafaxine-XR in treating major depressive disorder. METHODS A cost effectiveness analysis, using a decision tree modelled outpatient treatment over 6 months. Analytic perspectives were those of society (all direct and indirect costs) and the Ministry of Health of ...

Journal: :Applied and environmental microbiology 2010
David Runquist Bärbel Hahn-Hägerdal Maurizio Bettiga

Baker's yeast (Saccharomyces cerevisiae) has been genetically engineered to ferment the pentose sugar xylose present in lignocellulose biomass. One of the reactions controlling the rate of xylose utilization is catalyzed by xylose reductase (XR). In particular, the cofactor specificity of XR is not optimized with respect to the downstream pathway, and the reaction rate is insufficient for high ...

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