Three new eremophilane sesquiterpenes (1-3) were isolated from the mangrove endophytic fungus Xylaria sp. BL321 together with 07H239-A (4), a known analogue of the new compounds. The structures of these compounds were elucidated by analysis of their MS, 1D and 2D NMR spectroscopic data. Compound 4 showed activation activity on α-glucosidase at 0.15 μM (146%), and then, 4 gradually produced inhi...

Cyclotripeptide X-13 is a core of novel marine compound xyloallenoide A isolated from mangrove fungus Xylaria sp. (no. 2508). We found that X-13 dose-dependently induced angiogenesis in zebrafish embryos and in human endothelial cells, which was accompanied by increased phosphorylation of eNOS and Akt and NO release. Inhibition of PI3K/Akt/eNOS by LY294002 or L-NAME suppressed X-13-induced angi...

Chemical investigations of the fermentation broth from the microfungus Xylaria sp. have afforded the new natural product 3-chloro-4-hydroxyphenylacetamide 1 and the previously reported fungal metabolite 3-chloro-4-hydroxyphenylacetic acid 2. This paper reports the isolation and full spectroscopic characterisation of compounds 1 and 2 by NMR, UV, IR and MS data. The crystal structure and one-pot...

Abstract Lobster is a leading commodity in Aceh Province and it one of the commodities with high economic price. Besides, believed that Jaya Regency has superior fisheries commodities. This study aims to describe composition catch, relationship between length weight productivity catch on six different types lobster Jaya. The was conducted from June August 2022 waters Jaya, Setia Bakti District,...

Unsaturated aliphatic isobutylamides from Asteraceae, Rutaceae and Piperaceae are potential agents to control schistosomiasis. Affinin (N-isobutyl-2,6,8_decatrienamide) from Heliopsis longipes has strong molluscicidal activity against Physa occidentalis (LD5e ca 100 PM) and the cercariae of the fluke. The amide has also been shown to be present in Wedelia parviceps flowers.

Fatigue life and backface strain predictions in adhesively bonded joints. A. Graner Solana, A.D. Crocombe* and I.A. Ashcroft a Faculty of Engineering and Physical Sciences (J5), University of Surrey, Guildford, Surrey GU2 7XH, UK. b Wolfson School of Mechanical and Manufacturing Engineering, Loughborough University, Leicestershire LE11 3TU, UK * Corresponding author. Tel: +44 1483 689194 Fax: +...

The phytochemical studies of Eschweilera longipes Miers (Lecythidaceae) have led to the identification of a new triterpene 3beta, 24-dihydroxyfriedelane, the known 1beta, 2beta, 3beta, 19beta-tetrahydroxyurs-12-en-28-oic acid (1beta-hydroxyeucaphic acid) besides the saponin sitosterol 3betaO-betaD-glucopyranoside. The structures were established from the IR, NMR and mass spectra data including ...

Pestalafuranones A-E (compounds 1-5), five new 2(5H)-furanones, have been isolated from cultures of an isolate of Pestalotiopsis besseyi. The structures of these compounds were elucidated mainly by analysis of their NMR spectroscopic data and HRESIMS experiments. Pestalafuranones A-C (compounds 1-3) displayed weak inhibitory effects against HIV-1 replication in C8166 cells, whereas pestalafuran...