Dramatic changes occur in nuclear organization and function during the critical developmental transition from meiosis to mitosis. The Drosophila nuclear lamina protein YA binds to chromatin and is uniquely required for this transition. In this study, we dissected YA's binding to chromatin. We found that YA can bind to chromatin directly and specifically. It binds to DNA but not RNA, with a pref...

The induction of major histocompatibility complex class II gene expression is mediated by three DNA elements in the promoters of these genes (W, X, and Y boxes). The Y box contains an inverted CCAAT box sequence, and the binding activity to the CAAT box is mediated by factor NF-Y, which is composed of subunits NF-YA and NF-YB. We have found that transfection of either dbpA or dbpB (mYB-1) or bo...

The Alu Ya-lineage is a group of related, short interspersed elements (SINEs) found in primates. This lineage includes subfamilies Ya1-Ya5, Ya5a2 and others. Some of these subfamilies are still actively mobilizing in the human genome. We have analyzed 2482 elements that reside in the human genome draft sequence and focused our analyses on the 2318 human autosomal Ya Alu elements. A total of 147...

BACKGROUND Previous research indicates that younger adults (YA) can identify men's tendency to be aggressive based merely on their neutral expression faces. We compared older adults (OA) and YA accuracy and investigated contributing facial cues. METHOD In Study 1, YA and OA rated the aggressiveness of young men depicted in facial photographs in a control, distraction, or accuracy motivation c...

Makala haya yanalenga kuangazia mikakati ya kimawasiliano katika matangazo ngono salama. Masuala utangazaji wa mipira ni baadhi mada ambazo mwiko tamaduni nyingi. Hii changamoto inayowakumba wanaoandaa salama ili kukabiliana na hii kitamaduni. Usomi huu ulitathmini Durex mtandao Facebook fan page Kenya. Madhumuni yalikuwa: kuhakiki inayotumiwa Durex. Utafiti uliongozwa nadharia Uchanganuzi Haki...

Mtunzi wa kazi ya fasihi hususan riwaya na tamthilia, hutumia mbinu mahususi kuwasilishia matukio mawazo yanavyoshuhudiwa katika jamii. Mbinu hizo huteuliwa mtunzi kwa makusudi ili ujumbe unaokusudiwa kuwasilishwa kueleweka mwafaka hadhira. ni zile zinazojibainisha kitengo cha tamathali za usemi. Katika utafiti huu, inayozingatiwa kinaya ambacho huwasilisha kinyume matarajio. Utafiti huu unatuo...