Lung macrophages are an important defence against respiratory viral infection and recent work has demonstrated that influenza-induced macrophage PDL1 expression in the murine lung leads to rapid modulation of CD8+ T cell responses via the PD1 receptor. This PD1/PDL1 pathway may downregulate acute inflammatory responses to prevent tissue damage. The aim of this study was to investigate the mecha...

The original topological Aharonov-Casher (AC) effect is due to the interaction of the anomalous magnetic dipole moment (MDM) with certain configurations of electric field. Naively one would not expect an AC effect for a scalar particle for which no anomalous MDM can be defined in the usual sense. In this letter we study the AC effect in supersymmetric systems. In this framework there is the pos...

 Abstract—Mode division multiplexing (MDM) has the potential of increasing the capacity of optical fiber transmission system. However, primary impaired factor mode-dependent loss (MDL) poses fundamental performance limitations. Recently MIMO space time coding technique has provided a potential solution to mitigate the MDL and hence started receiving considerable interests. In this paper, ortho...

Neuronal damage in human immunodeficiency virus type 1 (HIV-1) infection in the brain is thought to occur at least in part through NMDA receptor (NMDAR) excitation initiated by soluble neurotoxins from HIV-infected brain macrophages. Furthermore, brain regions enriched in NMDAR-2A (NR2A) and NMDAR-2B (NR2B) subunits, such as the hippocampus, are particularly vulnerable. Using cultured rat hippo...

Magnesium (Mg) has drawn increasing attention as a tissue engineering material. However, there have been very few studies of laser-melted Mg-Zn alloys. In this study, four binary Mg-xZn (x = 2, 4, 6 and 8 wt. %) alloys were fabricated by laser melting. The influence of zinc (Zn) content and technique on the degradation behavior and mechanical properties of Mg were discussed. Results revealed th...

The alpine wetlands in the Qinghai-Tibetan Plateau have degraded recent decades. However, response of soil food web to degradation is still unclear. Four habitats including a wet meadow (WM), grassland (GM), moderately (MDM) and severely (SDM) (sandy meadows) were selected along degrees degradation. macrofaunal biomass environmental factors vegetation investigated. community increased significa...

Purpose To develop a particle transport code to compute w-values and stopping power of swift ions in liquid water gases interest for reference dosimetry hadrontherapy. analyze the relevance inelastic post-collisional processes considered. Methods The Monte Carlo MDM was extended case ion impact on (MDM-Ion). Relativistic corrections cross sections Auger emission were effects introducing differe...

We have reported previously that human alpha(1)-acid glycoprotein (AGP) inhibits the infection of human monocyte-derived macrophages (MDM) by R5 HIV-1, and that a disulphide-bridged peptide mimicking the clade B HIV-1 gp120 consensus V3 domain (V3Cs) binds specifically to CCR5 (the major co-receptor of R5 HIV strains) on these cells [Seddiki, Rabehi, Benjouad, Saffar, Ferriere, Gluckman and Gat...