Presently used single-needle air-driven droplet generators are incapable of producing sufficient numbers of islet-containing droplets in a sufficiently short time-period to allow for successfully grafting alginate-poly-L-lysine encapsulated islets in large animals or humans. We have designed an air-driven multineedle droplet generator, which increases the production rate by simultaneously produ...

Capsular contracture is a common complication after breast augmentation surgery. This study pathologically evaluated the soft-tissue response to surface modifications in both smooth and textured tissue expander prostheses. METHODS Smooth tissue expanders and textured tissue expanders in 5 cases each were used for breast reconstruction after mastectomy. Histological samples were harvested from...

Yunnan Baiyao is a well-known Chinese herbal medicine that has been used as a haemostatic drug for nearly 100 years. The aim of this clinical trial was to evaluate the efficacy and safety of Yunan Baiyao capsules on the reduction of blood loss in bimaxillary orthognathic surgery. 87 consecutive patients scheduled for simultaneous maxillary Le Fort I osteotomies and bilateral sagittal split ramu...

OBJECTIVE To validate a method for determining the simvastatin content of compounded capsules, using high performance liquid chromatography. METHODS Eighteen samples of simvastatin 40 mg capsules from compounding pharmacies in the cities of São Paulo, Guarulhos, São Bernardo do Campo and Campinas, Southeastern Brazil, prescribed for fictitious patients were assessed. The analyses were based o...

Heidelberger and Avery’s early experiments hinged on a simple element: nitrogen. Based on its presence or absence, the duo showed that the antibody-reactive substances on pneumococcal bacterial capsules were nitrogen-free carbohydrates, and that the reacting antibodies were nitrogencontaining proteins (see “How Heidelberger and Avery sweetened immunology” JEM 202:1306). The discovery that antib...

Heidelberger and Avery’s early experiments hinged on a simple element: nitrogen. Based on its presence or absence, the duo showed that the antibody-reactive substances on pneumococcal bacterial capsules were nitrogen-free carbohydrates, and that the reacting antibodies were nitrogencontaining proteins (see “How Heidelberger and Avery sweetened immunology” JEM 202:1306). The discovery that antib...

The recent preparation of levansucrase, like that of dextransucrase and phosphorylase, brings a new and powerful tool to bear on the study of macromolecular biosynthesis (Hestrin, Avineri-Shapiro & Aschner, 1943; Hestrin & Avineri-Shapiro, 1943; Hehre & Sugg, 1942; Stacey, 1942, 1943; cf. also Cori, 1939; Hanes, 1940; Behrens & Bergmann, 1939). Recent work on polysaccharide production in vitro ...

Vancomycin is used increasingly to treat invasive infections caused by multidrug-resistant Streptococcus pneumoniae. Although no vancomycin-resistant strains have been isolated to date, tolerant strains that fail to die rapidly and that cause relapsing disease have been described. The vex123-pep27-vncRS locus, consisting of an ABC transporter, a presumed signaling peptide, and a two-component s...

Large fluorescent molecules have been encapsulated in pyrogallol[4]arene nano-capsules, thus exploring the limits of molecular encapsulation; the orientation of these probe molecules within these nano-capsules has been examined with additional computational approaches in one case.

Microencapsulated Mitomycin C with ethylcellulose was infused into isolated dog kidneys through the renal artery. The capsules were lodged mainly at cortico-medullary junction, where the drug was released from the capsules. Vascularity of kidney was reduced moderately.