Tert-butyl carbazate (1) reacted with ammonium thiocyanate and phenyl isothiocyanate to afford the corresponding 5-tert-butoxy-4H-1, 2, 4-triazole-3-thiol (3) 5-tert-butoxy-4-phenyl-2H1, 2, 4-triazole-3(4H)-thione 5 respectively. Compound (1) also reacted with carbon disulfide and potassium hydroxide to afford 5-tert-butoxy-1, 3, 4-oxadiazole-2(3H)-thione 6. Treatment of 6 with methyl iodide, 2...

Displacement reaction of 2,3-dichloroquinoxaline with secondary amines in boiling ethanol afforded it`s mono aminoquinoxaline derivatives. Further reaction of the latter compounds with sodium azide in warm dimethylsulfoxide achieved a group of 4-amino tetrazolo[1,5-a]quinoxaline derivatives. 1HNMR spectra of these compounds are discussed.

Tetradentate complexes of Zn (II) Schiff bases derived from DHA, o-phenylenediamine, 4- N, Diethyl amino Salicylaldehyde (L1) and Dehydroacetic Acid (DHA), 4-methyl-o-phenylenediamine, 5-bromo (L2) have been synthesized characterized by elemental analysis, magnetic susceptibility, thermal X-ray diffraction, 1HNMR, Mass, IR,UV visible spectra conductometry. The ligand field parameters found to o...

a series of n-substituted-2,4-thiazolidinedione derivatives (tzds) were prepared via n-alkylation of 2,4-tzd at position 3 using substituted benzyl halides. synthesized n-substituted-2,4-tzd was then substituted at position 5 with substituted aromatic aldehyde according to knoevenagel condensation method. structures of the compounds were elucidated using various spectral techniques viz. ir, 1hn...

The aim of this study was to characterize the phytochemicals and investigate antimicrobial efficacy shade dried roots Asparagus adscendens. powder were extracted with chloroform after removal solvent under reduced pressure subjected for chromatographic separation. After column chromatography purification five compounds i.e .hexacosanyltriacontanoate, hexatriacontanone, 2,3,5,7-tetramethoxydi hy...

Coumarin derivatives have shown different biological activities, such as antifungal, antibacterial antiinflammatory, and antioxidant besides antibiotic resistance modulating effects, anti-HIV, hepatoprotective, antitumor effect. So, new coumarin (hydrazones an amide) were synthesized through multisteps reactions. All the target compounds characterized by FT-IR spectroscopy, 1HNMR analysis. The ...

New N-substituted ?-aminonitrile derivatives from menthol were synthesized by consecutive succinic ester formation, propargylation, 1,3-dipolar Huisgen cycloaddition and Strecker reaction. The structures of the compounds confirmed diverse spectroscopic techniques including 1HNMR, 13C-NMR, ESI-MS IR. novel evaluated for their in vitro antibacterial activities against Staphylococcus aureus as Gra...