Water and salt concentrations in an animal's body fluids can fluctuate with changing environmental conditions, posing osmoregulatory challenges that require behavioral and physiological adjustments. The purpose of this study was to investigate body water dynamics in the estuarine diamondback terrapin (Malaclemys terrapin), a species that undergoes seasonal dormancy in salt marsh habitats. We co...

Evaluation of body composition (BC) represents a valuable screening tool to assess nutritional status among diabetic patients. The most commonly used methods evaluate BC in the clinical practice are based on bicompartmental models such as dual energy X-ray absorptiometry (DXA) etc. Factors like daily caloric intake (DCI), percentage total water (%TBW), muscle mass and bone changes that occur th...

TO THE EDITOR—Sandri et al [1] recently reported important population pharmacokinetic data on intravenous polymyxin B in critically ill patients. They conclusively demonstrate that the dosage of polymyxin B should not be based on kidney function. Although no specific dosage regimen is recommended, the inference from this work is that polymyxin B should be dosed on total body weight (TBW). Unfor...

After being placed on extracorporeal life support (ECLS), newborn patients typically weight 5% to 30% more than their birthweight. Recovery and eventual decannulation from ECLS is associated with a return to baseline weight or birthweight values after a pronounced diuresis. It has been assumed that the increases in weight in these patients are due to increases in extracellular fluid (ECF) and t...

BACKGROUND The different effects of total body weight (TBW), fat-free mass (FFM), and fat mass (FM) on left ventricular (LV) geometry and function are complex. We investigated the associations of changes over time in TBW, FM, and FFM with changes in LV geometry and function. METHODS AND RESULTS We analyzed data from 1189 subjects (694 women), aged 44 to 86 years, from the baseline and the 5-y...

BACKGROUND Olecranon fracture (OF) is a common upper limb fracture, and the most commonly used techniques are still tension band wiring (TBW) and plate fixation (PF). The aim of the current study is to discuss whether TBW or PF technique of internal fixation is better in the treatment of OFs, using the method of meta-analysis. METHODS The eligible studies were acquired from PubMed, CNKI, Emba...

OBJECTIVES To assess the influence of abnormalities in fluid status and body composition on agreement between multifrequency bioimpedance analysis (MF-BIA), segmental BIA (sigmaBIA), the Watson formula, and tracer dilution techniques. DESIGN Cross-sectional. SETTING Multicenter. PATIENTS 40 patients (29 males, 11 females) on peritoneal dialysis (PD). MAIN OUTCOME MEASURES Agreement betw...

OBJECTIVE This study tested the hypothesis that bioelectrical impedance vectors, group and individual, are valid indicators of total body water (TBW) and hydration status in women experiencing fluid gain and loss during and after pregnancy. METHODS We measured TBW, assessed with D(2)O dilution, and resistance (R) and reactance (Xc), determined with 800 microA at 50 kHz and standardized for he...

The pharmacokinetic profile of ceftaroline has not been well characterized in obese adults. The purpose of this study was to evaluate the pharmacokinetics of ceftaroline in 32 healthy adult volunteers aged 18 to 50 years in the normal, overweight, and obese body size ranges. Subjects were evenly assigned to 1 of 4 groups based on their body mass index (BMI) and total body weight (TBW) (ranges, ...