Coronary artery ectasia (CAE) is a rare form of coronary artery disease. It has previously been shown that nitrate derivatives induce exertional angina in patients with CAE. Furthermore, there is limited data about the effects of other anti-ischemic agents in CAE. The aim of this study was to investigate the effect of trimetazidine on exercise performance in patients with CAE. The study populat...

We present a novel convolutional auto-encoder (CAE) for unsupervised feature learning. A stack of CAEs forms a convolutional neural network (CNN). Each CAE is trained using conventional on-line gradient descent without additional regularization terms. A max-pooling layer is essential to learn biologically plausible features consistent with those found by previous approaches. Initializing a CNN ...

The measurement of the thrombosis in myocardial infarction (TIMI) frame count is a simple method for evaluating coronary blood flow. Although it is well known that slow coronary flow is present in patients with coronary artery ectasia (CAE), the effects of coexisting stenosis and the severity of ectatic involvement on coronory flow have not been adequately studied. Thus, we examined (1) the eff...

background: whether coronary artery ectasia (cae) is a unique clinical finding or results from other clinical entities is still unknown. we aimed to determine the cae prevalence, investigate the relationship between cae and patients’ demographic and clinical characteristics, and assess the prognosis at follow-up in a sample of iranian population. methods: t otally, 10057 patients who underwent ...

The levels of degradation of cefetamet pivoxil (CAT), cefuroxime axetil (CAE), and cefpodoxime proxetil (CPD) in 0.6 M phosphate buffer (pH 7.4) and human intestinal juice (pH 7.4) at 37 degreesC over 24 h were compared. Significant differences in the time courses of degradation and in the patterns of degradation products were observed. (i) The relative proportions of the Delta2- and Delta3-cep...

PURPOSE To evaluate the safety and efficacy of ophthalmic MIM-D3, a tyrosine kinase TrkA receptor agonist, in patients with dry eye. DESIGN A prospective, two-center, randomized, double-masked, placebo-controlled Phase 2 study. METHODS A total of 150 dry eye patients were randomized 1:1:1 to study medication (1% MIM-D3, 5% MIM-D3, or placebo) and dosed twice daily (BID) for 28 days. Key eli...

While Computer-Aided Engineering (CAE) technology has revolutionized engineering analysis, design and research, its penetration into the undergraduate mechanical engineering curriculum has been limited. As a result, undergraduate students do not acquire a solid foundation in CAE technology that they can build upon during the course of their careers. Our pedagogical approach for integrating CAE ...

OBJECTIVE To investigate the incidence, imaging and clinical characteristics in elderly patients with coronary artery ectasia (CAE). METHODS A retrospective analysis was conducted on patients with CAE who underwent coronary angiography between January 2006 and December 2012. According to age, the enrolled patients were divided into two groups (elderly group, age ≥ 65 years; non-elderly group,...

In spite of the widespread use of CAD systems for design and CAE systems for analysis, the two processes are not well integrated because CAD and CAE models inherently use different types of geometric models and there currently exists no generic, unified model that allows both design and analysis information to be specified and shared. In this paper, a new approach called the CAD/CAE-integrated ...