The alternative sigma factor PvdS is required by Pseudomonas aeruginosa for initiation of transcription from pyoverdine (pvd) promoters. Two divergent PvdS-dependent promoters (pvdE and pvdF) were characterized by deletion analysis, and the minimal promoter region for each included a sequence element, the iron starvation (IS) box, that is present in other pvd promoters. Site-directed mutagenesi...

Animals sample their environment through sensory neurons with often elaborately branched endings named dendritic arbors. In a genetic screen for genes involved in the development of the highly arborized somatosensory PVD neuron in C. elegans, we have identified mutations in kpc-1, which encodes the homolog of the proprotein convertase furin. We show that kpc-1/furin is necessary to promote the ...

Neurons receive excitatory or sensory inputs through their dendrites, which often branch extensively to form unique neuron-specific structures. How neurons regulate the formation of their particular arbor is only partially understood. In genetic screens using the multidendritic arbor of PVD somatosensory neurons in the nematode Caenorhabditis elegans, we identified a mutation in the ER stress s...

The objective of this study was to characterize the species composition and functional potential vaginal uterine microbiota at 1 wk postpartum in dairy cows diagnosed with or without purulent discharge (PVD) 3 postpartum. hypothesis that differences between (PVD+) (PVD−) PVD were dependent on parity breed. Cytobrush samples vagina uterus collected from 36 Holstein-Friesian (7 primiparous 29 mul...

The paper summarizes the current development of high-velocity oxygen–fuel coupled physical vapor deposition (HVOF-PVD) duplex coatings as protective candidates. Following a detailed historical overview HVOF and PVD technologies, fabrication methods for are presented. coating superimposes synergistic advantages deposited by PVD, where traditional weaknesses each technique modified to great certa...

Peripheral Vascular Disease (PVD) is a progressive and chronic disease resulting from atherosclerotic events. Atherosclerotic obstructions are consequence of chronic ischemia in the lower extremity arteries in patients with PVD. It is suggested that blood levels of Matrix Metalloproteinases (MMPs) and endogenous Tissue inhibitors of Metalloproteinases (TIMPs) have been associated with atheroscl...

Introduction Given the frequency of renal functional impairment in patients with peripheral vascular disease (PVD) and concerns about nephrogenic systemic fibrosis, there is growing interest in unenhanced MRA (1,2). While promising, existing unenhanced MRA methods suffer from limitations that preclude robust clinical application for PVD. An ideal unenhanced method should be fast, easy to use, a...

background: the aim of this study was to evaluate the impact of diabetes mellitus (dm) on peripheral vascular disease (pvd) in patients with coronary artery disease (cad). methods: a total of 13702 consecutive patients who underwent coronary artery bypass grafting (cabg) at tehran heart center between january 2002 and march 2007 were included in this study. the demographic data, pvd, and outcom...

AIM To establish whether the presence of a retinal break can be predicted either by the presence of a positive Shafer's sign (pigment granules in the anterior vitreous) or symptomatology in patients presenting with an acute posterior vitreous detachment (PVD). METHODS 200 eyes of 200 phakic patients with a symptomatic PVD of less than 1 month's duration underwent documentation of symptomatolo...

OBJECTIVE To investigate the natural history and predictors of outcome of posthaemorrhagic ventriculomegaly in the very low birthweight (VLBW) infant. METHODS All VLBW infants admitted between September 1994 and September 1997 to the neonatal intensive care units of Brigham and Women's Hospital (Boston), Children's Hospital (Boston), and Christchurch Women's Hospital (New Zealand) with germin...