INTRODUCTION We report the case of a patient with antepartum HELLP syndrome and simultaneous rupture of the right liver lobe. An emergency caesarean section was performed and the liver rupture was managed surgically via perihepatic packing. The mother and her child recovered well and were discharged 19 days after admission. CASE REPORT We describe a case report and review the literature. Base...

BACKGROUND Altered maternal inflammatory responses play a role in the development of preeclampsia and the hemolysis, elevated liver enzymes and low platelets (HELLP) syndrome. We examined whether allelic variants of the innate immune receptors Toll-like receptor 4 (TLR4) and nucleotide-binding oligomerization domain 2 (NOD2), that impair the inflammatory response to endotoxin, are related to pr...

BACKGROUND Hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome is a severe condition of pregnancy that is associated with significant morbidity and mortality. Corticoteroid (CORT) therapy is common in the management of HELLP syndrome. This study evaluates the efficacy of CORT therapy to patients with HELLP Syndrome. MATERIAL AND METHODS A literature search was carried out...

BACKGROUND HELLP syndrome (a combination of hemolysis, elevated liver enzyme levels, and low platelet count) is a severe variant of preeclampsia that generally occurs before delivery but can occur post partum. This syndrome is more common than eclampsia and frequently leads to devastating neurological consequences such as intracerebral hemorrhage. OBJECTIVE Although mentioned in the obstetric...

Introducción. El síndrome de HELLP es una variante grave la preeclampsia, con baja incidencia, entre el 0,5-0,9 % todos los embarazos. La ruptura hepática espontánea en embarazo infrecuente, presenta alta mortalidad, y se ha relacionado hemangiomas hepáticos, coriocarcinoma HELLP.
 Caso clínico. Mujer 29 años 34,3 semanas, actividad uterina progresiva, sufrimiento fetal agudo hallazgos com...

abstract the first time weinstein in 1982 described patients with the syndrome of hemolysis, elevated liver enzymes, and low platelet count (hellp) in pregnant preeclamptic and eclamptic patients. this syndrome is a severe form of preeclampsia or eclampsia. usually hellp syndrome occurs at the third trimester and only 15% occur before the 27th week of pregnancy and rarely before the 20th week o...

Recent studies showed that considerable amounts of glycosaminoglycans are released into maternal blood during normal pregnancy and in hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome. Maternal endothelia and the syncytiotrophoblast layer have been discussed as a possible origin of these glycocalyx components. Our study aimed to visualize the glycocalyx on the syncytiotropho...

Preeclampsia is a relatively common hypertensive disorder during pregnancy. Preeclampsia occurs in about 5%15% of all pregnant women, may cause dangerous complication and even death in the mother and fetus (1). In 5% of all cases, preeclampsia can progress toward eclampsia, and up to 19% of the cases present with HELLP syndrome, maternal and perinatal mortality can be increased (2). Severe pree...

Severe maternal thrombocytopenia resulting in hemorrhage is often associated with high mortality. Three cases of severe maternal thrombocytopenia in association with heparin-induced thrombocytopenia (HIT), HELLP syndrome, and systemic lupus erythematosus (SLE) were successfully managed using intravenous immunoglobulin (IVIG). IVIG can reduce the severity of thrombocytopenia and hemolysis, stabi...

Objetivo: Analisar as diferentes condutas terapêuticas, relacionadas principalmente ao uso de corticosteroides, a serem tomadas diante um paciente com síndrome HELLP. Métodos: Esta revisão bibliográfica integrativa utilizou o PubMed, Cochrane e Science Direct como plataformas eletrônicas pesquisa, elegendo artigos publicados entre os anos 2002 2021. Os descritores utilizados foram “HELLP syndro...