The effect troponin I phosphorylation has on the Ca2+-binding properties of troponin C (TnC) in the whole troponin complex reconstituted from cardiac troponin I (TnI), troponin T, and TnC has been measured. To selectively follow Ca2+ binding at the Ca2+-specific sites of TnC, this subunit was labeled with the fluorescent probe 2-(4’-iodo-acetamidoanilino)naphthalene-6sulfonic acid before recons...

in this article the relationship between the amount of seasonal rainfall (autumn, winter and spring) and climate indices in iran have been studied. the climate indices (the southern oscillation(soi),the north atlantic oscillation(nao), arctic oscillation(ao),nino 3/4,the multivariate enso index(mei),trans_ nino index(tni) and the pacific decadal oscillation(pdo) are used as independent variable...

2014 The anchoring strength coefficient B is measured as a function of temperature using a Freedericksz technique in a very thin (l 2.5 03BCm) surfactant-treated cell of methoxybenzylidene butylaniline (MBBA). In the nematic phase this parameter varies from approximately 0.065 to 0.013 erg/cm2 for TNI 20 °C T TNI. The relationship between B and the nematic order parameter is discussed. J. Physi...

We report the determination of the Kerr constant (B) and the real part of the third-order nonlinear optic susceptibility (chi(3)) above the nematic-isotropic phase transition temperature (TNI) of a liquid crystal composed of bent-shaped molecules. The values of B and chi(3) just above (approximately 0.3 degrees C) TNI are approximately 8x10(-12) m/V2 and 5x10(-20) m2/V2, respectively. The estim...

We have analyzed one of the nine complementation groups that constitute the haplolethal (HL) region of the Shaker gene complex (ShC). Five mutations, including a dominant lethal, define this complementation group: HL I. Mutant phenotypes show abnormal embryogenesis with structural defects in the nervous system and aberrant degeneration of specific adult muscles in addition to altered action pot...

Impaired muscle function (fatigue) may result, in part, from modification of contractile proteins due to inadequate O(2) delivery. We hypothesized that severe hypoxemia would modify skeletal troponin I (TnI) and T (TnT), two regulatory contractile proteins, in respiratory muscles. Severe isocapnic hypoxemia (arterial partial pressure of O(2) of approximately 25 Torr) in six pentobarbital sodium...

Troponin is the key component of the calciumdependent switch of the contractile apparatus in striated muscle. There are three subunits of troponin: troponin C, a Ca -binding calmodulin-like protein; troponin T, which attaches the complex to tropomyosin, anchoring it to the thin filament as well as having a regulatory role; and troponin I (TnI), named for its ability to inhibit actin-myosin inte...