MOTIVATION Multilayer perceptrons (MLP) represent one of the widely used and effective machine learning methods currently applied to diagnostic classification based on high-dimensional genomic data. Since the dimensionalities of the existing genomic data often exceed the available sample sizes by orders of magnitude, the MLP performance may degrade owing to the curse of dimensionality and over-...

The muscle LIM protein (MLP) is a muscle-specific LIM-only factor that exhibits a dual subcellular localization, being present in both the nucleus and in the cytoplasm. Overexpression of MLP in C2C12 myoblasts enhances skeletal myogenesis, whereas inhibition of MLP activity blocks terminal differentiation. Thus, MLP functions as a positive developmental regulator, although the mechanism through...

Glomerulus segmentation in kidney tissue segments is a crucial nephropathology process used to diagnose renal diseases effectively. This study proposes novel and robust application of MLP (Multi-Layer Perceptron) based architectures for the glomeruli PAS (Periodic AcidSchiff) stained whole images effective diagnosis diseases. For challenge, proposed unique solution uses MLP-UNet Perceptron U-Ne...

We have previously introduced the Gamma MLP which is defined as an MLP with the usual synaptic weights replaced by gamma filters and associated gain terms throughout all layers. In this paper we apply the Gamma MLP to a larger scale speech phoneme recognition problem, analyze the operation of the network, and investigate why the Gamma MLP can perform better than alternatives. The Gamma MLP is c...

در میان شبکۀ معابر شهری، راه‌های اضطراری امدادرسانی حین زلزله، به‌ویژه مرحلۀ پاسخ به بحران، نقش مهمی ایفا می‌کنند. حفظ عملکرد این شبکه از معابر، ساعات اولیۀ پس اهمیت بسزایی دارد. محافظت و مقاوم‌سازی اجزای آسیب‌پذیر شبکه، به‌خصوص پل‌ها، پیش وقوع تأثیر شایان توجهی کاهش خسارات آسیب‌ها اغلب اوقات تمامی آسیب‌پذیر، به‌دلیل محدودیت بودجه، عملاً ناممکن است. ایجاب می‌کند که با شناسایی دقیق گزینه‌های ابتد...

Deviating from the conventional Hidden Markov ModelMulti-Layer Perceptron (HMM-MLP) hybrid paradigm of using MLP for classi cation, the proposed discriminative MLP technique uses MLP as a mapping module for feature extraction for conventional HMM-based systems. The MLP is discriminatively trained on the phonetically labeled training data to generate the phoneme posterior probabilities. We achie...

BACKGROUND The cardiac LIM domain protein MLP, a member of the cysteine-rich protein family, is an essential regulator of cardiac muscle development. Mice with a disruption of the MLP gene resemble the morphological and clinical picture of dilated cardiomyopathy and heart failure in humans. We investigated whether altered MLP expression is significant for the pathogenesis of human heart failure...