Type 1 fimbrial phase-locked mutants of uropathogenic Escherichia coli cystitis isolate F11 were used to assess the role of the invertible element during urinary tract infection. Compared to the wild type, the phase-locked off mutant was attenuated, and constitutive production of type 1 fimbriae by the phase-locked on mutant did not provide a competitive advantage.

Hydrographic and tracer [chlorofluorocarbon (CFC), component F11] data in the tropical Atlantic off Brazil taken in spring 1994 are used to describe the development of the water mass characteristics of Antarctic Bottom Water (AABW) between 10°S and 11°N. To compute the AABW transports, geostrophic computations and directly measured velocity fields are combined. Velocity profiles were measured w...

Using a three-sector general equilibrium model with non-traded goods, we investigate the impact of foreign direct investment on the real wages of skilled and unskilled workers. We show that foreign direct investment increases the real wages of skilled and unskilled workers, but widens the gap between the two under plausible conditions. JEL: F10, F11, F21

The whole-cell patch-clamp technique was used to record Ba2+ currents through voltage-activated calcium channels in the clonal dorsal root ganglion cell line F11-B9. The pain-producing peptide bradykinin (BK; 100 nM) reduced the sustained Ba2+ current in F11-B9 cells by 30%. In cultures prelabeled with 3H-arachidonic acid and tested under ionic conditions similar to those used for recording Ba2...

Oligopeptides incorporating N3-(4-methoxyfumaroyl)-L-2,3-diaminopropanoic acid (FMDP), an inhibitor of glucosamine-6-phosphate synthase, exhibited growth inhibitory activity against Candida albicans, with minimal inhibitory concentration values in the 0.05-50 μg mL-1 range. Uptake by the peptide permeases was found to be the main factor limiting an anticandidal activity of these compounds. Di- ...

The Middle East respiratory syndrome coronavirus (MERS-CoV) has infected more than 1900 humans, since 2012. The syndrome ranges from asymptomatic and mild cases to severe pneumonia and death. The virus is believed to be circulating in dromedary camels without notable symptoms since the 1980s. Therefore, dromedary camels are considered the only animal source of infection. Neither antiviral drugs...

BackgroundCoagulation factor XI (FXI) is a plasma serine protease zymogen that contributes to hemostasis. However, the mechanism of its secretion remains unclear.ObjectiveTo determine molecular FXI by characterizing novel mutant identified in FXI‐deficient Japanese patient.Patient/MethodsThe gene (F11) was analyzed direct sequencing. Mutant recombinant (rFXI) overexpressed HEK293 or COS‐7 cells...

Several research programmes have demonstrated how Transcranial Ultrasound Stimulation (TUS) can non-invasively and reversibly mechanically perturb neuronal functions. However, the mechanisms through which such reversible a priori non-damaging behaviour be observed remain largely unknown. While several TUS protocols motor behavioural alterations in vivo models, vitro studies scarce. In particula...

The main purpose of this research was to determine the influence a therapeutic dose an opioid drug (methadone) on selected auditory functions in patients addicted opioids (recognition ICD-10; F11) and undergoing substitution therapy. Various hearing tests were used – pure tone audiometry, impedance otoacoustic emission measurement, speech noise test two sessions, before after methadone intake. ...