AIMS Recent evidence suggests that intake of excessive dietary fat, particularly saturated fat and trans-hydrogenated oils (trans-fatty acids: TFA) can impair learning and memory. Central obesity, which can be induced by neonatal injections of monosodium Glutamate (MSG), also impairs learning and memory. To further clarify the effects of dietary fat and MSG, we treated C57BL/6J mice with either...

Introduction: Monosodium glutamate (MSG) is one of the commonest food additives in modern nutrition. Recent studies showed the modulatory effect of MSG on rat thymocyte apoptosis in vivo and under in vitro conditions. However, the influence of MSG on thymocyte proliferation is largely unknown. Material and methods: We evaluated the effect of increased MSG concentrations on thymocyte proliferati...

Major surface glycoprotein (Msg), the most abundant cell surface protein of Pneumocystis, plays an important role in the interaction of this opportunistic pathogen with host cells, and its potential for antigenic variation may facilitate evasion of host immune responses. In the present study, we have identified and characterized the promoter region of msg in 3 species of Pneumocystis: P. carini...

Suckling-age rats display endogenous circadian rhythmicity of metabolic rate (MR) with energy-saving, torpor-like decreases, which are sympathetically controlled and suppressed by leptin treatment. We investigated whether neonatal monosodium glutamate (MSG) treatment, known to cause arcuate nucleus damage and adult-age obesity, alters energy balance in the first two postnatal weeks. Continuousl...

Suckling-age rats display endogenous circadian rhythmicity of metabolic rate (MR) with energysaving, torpor-like decreases which are sympathetically controlled and suppressed by leptin treatment. We investigated whether neonatal monosodium glutamate (MSG) treatment, known to cause arcuate nucleus (ARC) damage and adult-age obesity, alters energy balance in the first two postnatal weeks. Continu...

Monosodium L glutamate (MSG) has been known and used to stop focal bleeding in remoted area and around battle fields along Thai-Laos-Cambodian border. The hemostatic effect of MSG was studied by Jaiarj eta/ (l985a). It was found that MSG decreased the bleeding times of the wounds made by excising the tails or by incising the femoral veins ofWistar rats. In an in vitro study with human blood, th...

It is well known that adrenalectomy (ADX) reverses the eating and energy balance disturbances in a variety of models of obesity associated with elevated food intake. We have previously demonstrated enhanced functional activity in the small intestine of neonatally monosodium glutamate-treated (MSG) obese rats despite the absence of overeating and we concluded that these changes might also contri...

Siberian hamsters (Phodopus sungorus) have the ability to express daily torpor and decrease their body temperature to approximately 15 degrees C, providing a significant savings in energy expenditure. Daily torpor in hamsters is cued by winterlike photoperiods and occurs coincident with the annual nadirs in body fat reserves and chronic leptin concentrations. To better understand the neural mec...

OBJECTIVE To study two different models of obesity, exocrine and endocrine, and its association on tail arterial pressure (TAP), body weight (BW), glucose metabolism and visceral fat content. METHODS Male Wistar rats were studied. The MSG group was composed by rats that received of MSG in neonatal period. At the 3rd month of life, part of these animals received cafeteria diet. Animals receive...