Amide proton transfer (APT) imaging is a novel MRI technique, in which the amide protons of endogenous proteins and peptides are irradiated to accomplish indirect detection using the bulk water signal. In this paper, the APT approach was added to a standard brain MRI protocol at 3T, and twelve patients with high-grade gliomas confirmed by histopathology were scanned. It is shown that all tumors...

BACKGROUND Antiphospholipid antibodies are associated with recurrent fetal loss, but the clinical relevance of antiprothrombin (aPT) antibodies remains controversial. This study was designed to evaluate the relationship of plasma concentrations of aPT antibodies (IgG, IgM, and IgA isotypes) and recurrent spontaneous abortion (RSA) not associated with antiphospholipid-antibody syndrome. METHOD...

BACKGROUND The optimal antiplatelet therapy (APT) treatment strategy after Coronary Artery Stenting (CAS) in non-cardiac surgery, such as total knee arthroplasty (TKA) or urgent TKA-related surgery remains unknown. METHODS We built a decision tree model to examine the mortality outcomes of two alternative strategies for APT after CAS use in the perioperative period namely, continuous use and ...

We propose a class of synthetic optical materials in which the refractive index satisfies n(−x) = −n∗(x). We term such systems antisymmetric parity-time (APT ) structures. Unlike PT -symmetric systems, which require balanced gain and loss, i.e., n(−x) = n∗(x), APT systems consist of balanced positiveand negative-index materials. Despite the seemingly PT -symmetric optical potential V (x) ≡ n(x)...

A decade ago, atom probe tomography (APT) was applied almost exclusively to the study of metals, since the study of materials with lower conductivities, such as semiconductors, was considered pragmatically to be very difficult. The advent of commercially-available laser-pulsed APT systems has since enabled the increasingly widespread application of APT to semiconductors, with particularly notab...

Stent thrombosis (ST) is a severe and feared complication of coronary stenting. Patients who have suffered from ST are usually treated according to the "one-size-fits-all" dosing regimen of aspirin and clopidogrel. Many ST patients show high on-treatment platelet reactivity (HPR) despite this antiplatelet therapy (APT). It has been shown that HPR is a risk factor for major adverse cardiac event...

Analysis of patterns in time (APT) is a method for gathering information about observable phenomena such thatprobabilities of temporalpatterns of events can be estimated empirically. If appropriate sampling strategies are employed, temporal patterns can be predicted from APT results. As an example of the fruitfulness of APT, it was discovered in a classroom observational study that elementary s...

Attapulgite (APT) has been frequently used for the adsorptive removal of dyes from aqueous solution owing to its unique one-dimensional nanoscale structure and low-cost, abundant, eco-friendly advantages. In this work, APT was functionalized under mild hydrothermal condition using chloroacetic acid (CA) with COOH functional groups to improve its adsorption properties. The effect of hydrothermal...

We have discovered that the bacterial toxins aerolysin and pertussis toxin share a common domain. This is surprising because the two toxins affect cells in very different ways. The common domain, which we call the APT domain, consists of two three-stranded antiparallel beta-sheets that come together and wrap around a central pair of helices. The APT domain shares a common fold with the C-type l...

Atom probe tomography (APT) data acquired from a CAMECA LEAP 4000 XHR for the CdS/CdTe interface for a non-CdCl2 treated CdTe solar cell as well as the mass spectrum of an APT data set including a GB in a CdCl2-treated CdTe solar cell are presented. Scanning electron microscopy (SEM) data showing the evolution of sample preparation for APT and scanning transmission electron microscopy (STEM) el...