This letter addresses how to set SIR targets higher than normally required, in order to mitigate the effect of signal-to-interference ratio (SIR) measurement error included in power control steps. We find that scaling up the SIR targets by 1 dB is conformable to resisting SIR measurement error for code division multiple access (CDMA) mobile systems. key words: SIR target setting, CDMA mobile sy...

FoxO transcription factors and sirtuin family deacetylases regulate diverse biological processes, including stress responses and longevity. Here we show that the Caenorhabditis elegans sirtuin SIR-2.4--homolog of mammalian SIRT6 and SIRT7 proteins--promotes DAF-16-dependent transcription and stress-induced DAF-16 nuclear localization. SIR-2.4 is required for resistance to multiple stressors: he...

The conserved DAF-16/FOXO transcription factors and SIR-2.1/SIRT1 deacetylases are critical for diverse biological processes, particularly longevity and stress response; and complex regulation of DAF-16/FOXO by SIR-2.1/SIRT1 is central to appropriate biological outcomes. Caenorhabditis elegans Host Cell Factor 1 (HCF-1) is a longevity determinant previously shown to act as a co-repressor of DAF...

BACKGROUND We conducted a large national cohort study to examine the risk of cancer among men and women with genital warts (GW). METHODS By use of the Danish National Patient Register, we identified 16,155 men and 32,933 women who received a diagnosis of GW during 1978-2008. Standardized incidence ratios (SIRs) were computed as estimates of the relative risk of specific cancers or sites. RE...

Gac Sanit. 2005;19(5):417-9 a Sir Autin Bradford Hill que ha seguido dando frutos hasta hace bien poco. El abandono del tabaquismo por la mayoría de los médicos ingleses, entre los que se contaba él mismo, fue el primer paso de una contribución que ha evitado millones de muertes prematuras. Exploró la relación del tabaco con el cáncer de vejiga y otros cánceres y con las enfermedades cardiovasc...

There are times when something is simply so familiar that we can no longer see it at all. It can be a story, or a concept, or even a flesh-and-blood person. Familiarity breeds not only contempt, but a kind of invisibility as well. For too many of us, such is the case with Sir William Osler. In his time (1849–1919), many considered him to be one of the greatest practitioners, teachers, and write...