Observations and interpretation of extragalactic rotational and rovibrational H2 emission are reviewed. Direct observations of H2 lines do not trace bulk H2 mass, but excitation rate. As such, the H2 lines are unique diagnostics, if the excitation mechanism can be determined, which generally requires high-quality spectroscopy and suitable additional data. The diagnostic power of the H2 lines is...

In H2-DM mutant mice, most MHC class II molecules are bound by a single peptide, CLIP, derived from the class II-associated invariant chain. Previous studies showed that H2-DM- cells are defective in presenting synthetic peptides to class II-restricted T cells. In sharp contrast, however, the same peptides elicited strong CD4+ T cell responses in H2-DM- animals. We now provide an explanation fo...

Despite insufficient laboratory data, radiotherapy after intratumoral injection of hydrogen peroxide (H2 O2 ) is increasingly being used clinically for radioresistant tumors. Especially, this treatment might become an alternative definitive treatment for early and advanced breast cancer in patients who refuse any type of surgery. The purpose of this study was to investigate the biological effec...

The production of hydrogen (H2) is an inherent component of biological dinitrogen (N2) fixation, and there have been several studies quantifying H2 production relative to N2 fixation in cultures of diazotrophs. However, conducting the relevant measurements for a field population is more complex as shown by this study of N2 fixation, H2 consumption and dissolved H2 concentrations in the oligotro...

We investigated the mechanism that TGF-beta1 influences the immuno-environment at maternal-fetal interface and affects embryo implantation, using mouse uterine horn injection model. The expression of MHC I antigen (H2-D1) and the chaperone of MHC II antigen (H2-DM) after anti-TGF-beta1 antibody or hrTGF-beta1 treated pregnant mice were examined by real-time PCR, western blotting and immunohisto...

Molecular hydrogen (H2) has been reported to be effective for a variety of disorders and its effect has been ascribed to a selective scavenge of hydroxyl radicals (•OH) at the beginning. Consumption of H2 was either by inhalation, drinking H2-containing water (H2 water), or infusion of H2-containing saline. Among various disorders, animal model of ischemic injury and Parkinson’s disease showed ...

This paper is concerned with the mixed H2/H∞ control problem via static output feedback control. The main purpose of this paper is to give an iterative method for finding a sub-optimal static output-feedback controller for the mixed H2/H∞ control problem. The contribution of this paper is to derive a gradient of the H2 cost function. Using this gradient, we propose a gradient method for H2 and ...