Internalization of nano- and microparticles into live cells correlates closely with their potential applications, functions, cytotoxicity and intracellular drug delivery. Particularly, delivery of a large variety of cargoes such as proteins, peptides, nucleic acids and small particles into cells could be enhanced by some ligands such as Tat peptide. In this work, the ability of Tat mediated cel...

A b s t r a c t L i q u i d u s phase relationships in the system MgSiO3-SiO2 at 5.0 GPa have been determined using a multianvil apparatus. Compared to phase relationships at 1 atm, the MgSiO3-SiO2 phase diagram at 5.0 GPa is significantly different in two respects. First, the composition of the eutectic between MgSiO3 and SiO2 moves from 65.0 wt% SiO2 at 1 atm/1547°C (protoenstatite-cristobali...

Silicon carbide (SiC) has shown considerable potential for ultraviolet (UV) photode‐ tectors due to its properties such as wide band gap (3.26 eV for 4H-SiC), high break down electric field and high thermal stability. 4H-SiC-based UV photodetectors such as Schottky, metal-semiconductor-metal (MSM), metal-insulator-semiconductor (MIS) and avalanche have been presenting excellent performance for ...

BACKGROUND Head and neck squamous cell carcinoma (HNSCC) is currently the eighth leading cause of cancer death worldwide. The often severe side effects, functional impairments and unfavorable cosmetic outcome of conventional therapies for HNSCC have prompted the quest for novel treatment strategies, including the evaluation of nanotechnology to improve e.g. drug delivery and cancer imaging. Alt...

A new simple and cheap method to grow large scale SiC-SiO2 nanocables on catalyzed Si substrate directly is presented. The method is based on the thermal decomposition of methanol. The grown nanocables consisted of crystalline 3C-SiC and amorphous SiO2. A simple etching and oxidation process was used to analyze the contribution of SiC and SiO2 components to photoluminescence.

Covalent labeling of solvent exposed amino acid residues using chemical reagents/crosslinkers followed by mass spectrometric analysis can be used to determine the solvent accessible amino acids of a protein. A variety of chemical reagents containing cleavable bonds were developed to label abundantly found lysine residues on the surface of protein. To achieve efficient separation of labeled pept...

Humans may be exposed to engineered silica nanoparticles (SiO2-NPs) but potential adverse effects are poorly understood, in particular in relation to cellular effects and modes of action. Here we studied effects of SiO2-NPs on cellular function in human hepatoma cells (Huh7). Exposure for 24 h to 10 and 50 μg/ml SiO2-NPs led to induction of endoplasmic reticulum (ER) stress as demonstrated by t...

the aims of the study were to investigate the effect of poly(ε -caprolactone) (pcl) and nano- sio2 within the thermoplastic starch (tps) blends on the rate and extent of starch enzymatic hydrolysis using enzymes α-amylase and amyloglucosidase. the results of this study have revealed that blends with nano-sio2 content at 6 wt% exhibited a significantly reduced rate and extent of starch hydrolysi...