BackgroundCommon femoral artery (CFA) disease is often heavily calcified and prone to low patency rates with endovascular treatment compared surgical endarterectomy. Recent data suggest promising short-term outcomes the adjunct use of intravascular lithotripsy; however, on its midterm effectiveness are lacking. We clinically driven target lesion revascularization (CD-TLR) between patients recei...

Malignant glioma cells maintain an elevated intracellular pH (pH(i)) within hypoxic-ischemic tumor microenvironments through persistent activation of sodium-proton transport (McLean et al., 2000). Amiloride has been reported to selectively kill human malignant glioma cell lines but not primary astrocytes (Hegde et al., 2004). While amiloride reduces pH(i) of malignant gliomas by inhibiting isof...

OBJECTIVE The study sought to compare angiographic and clinical outcomes of new-generation drug-eluting stents (DES) versus drug-coated balloon (DCB) in patients with coronary in-stent restenosis (ISR). DESIGN Meta-analysis using data from randomised trial found by searches on PubMed, the Cochrane Library, ClinicalTrials.gov and websites of major cardiovascular congresses. SETTING Only rand...

PURPOSE Nitroglycerin may improve the response to chemotherapy in advanced non-small cell lung cancer. The effects and mechanisms of nitroglycerin on the enhancement of chemosensitivity to docetaxel and carboplatin regimen (DCb) in patients with lung adenocarcinoma have not been reported. EXPERIMENTAL DESIGN Seventeen patients with operable lung adenocarcinoma and stable angina pectoris were ...

BACKGROUND Randomized controlled trials have reported favorable 1-year outcomes with drug-coated balloons (DCBs) for the treatment of symptomatic peripheral arterial disease when compared with standard percutaneous transluminal angioplasty (PTA). Evidence remains limited on the durability of the treatment effect with DCBs in the longer term. METHODS AND RESULTS IN.PACT SFA is a single-blind, ...

OBJECTIVES The purpose of this study was to assess the safety and performance of Stellarex Drug-coated balloon (DCB). BACKGROUND DCB coatings differ in excipients, paclitaxel dose, and coating morphologies. Due to these differences, a class effect with DCBs has not been demonstrated. Consequently, each DCB needs to be evaluated independently based on its own clinical study results. METHODS ...

Strain DCB-1 is a strict anaerobe capable of reductive dehalogenation. We elucidated metabolic processes in DCB-1 which may be related to dehalogenation and which further characterize the organism physiologically. Sulfoxy anions and CO2 were used by DCB-1 as catabolic electron acceptors. With suitable electron donors, sulfate and thiosulfate were reduced to sulfide. Sulfate and thiosulfate supp...

IXYS announced that in keeping up with ambitious growth plans in the IGBT market, its European Operation, a leader in Direct Copper Bond (DCB) module packaging technology, located in Lampertheim, Germany has extended its portfolio of IGBT modules down in power to cover the high volume cost sensitive segment of the market. This new family of DCB based IGBT Modules are housed in the industry stan...