Ataxia, a gross lack of motor control, is symptomatic of broader neurological disorder, typically of the cerebellum. A few case reports have documented the association of primate erythroparvovirus 1 [more commonly known as human parvovirus B19 (B19)] with ataxia. Parvoviruses are small DNA viruses that infect many different species. B19 is a well-known cause of erythema infectiosum, a common ra...

background: parvovirus b19 (b19) is the only member of the family parvoviridae associated with human infection. al­though there are some studies to estimate the immunity to parvovirus in various populations but there is no seroepidemiologi­cal sur­vey from iran until now thus the age-specific immunity to human parvovirus infection was esti­mated. methods:  a subset sample of 1500 study subjects...

Increased recognition of parvovirus B19 (B19), an erythrovirus, as a significant human pathogen that causes fetal loss and severe disease in immunocompromised patients has resulted in intensive efforts to understand the pathogenesis of B19-related disease, to improve diagnostic strategy that is deployed to detect B19 infection and blood-product contamination and, finally, to elucidate the natur...

Kidney transplant (KT) recipients can develop symptomatic Parvovirus (PV) B19 infections, frequently associated with persistent anemia. The aim of this study was to evaluate the prevalence and clinical significance of PV B19 infection in anemic and non-anemic KT patients. Overall, out of 64 patients monitored for the presence of PV B19 by real-time PCR, 2 (3.12%) had an active PV B19 infection,...

Parvovirus B19 infects predominantly erythroid cells, leading to transient inhibition of erythropoiesis. Immunocompromised patients may be unable to produce neutralizing antibodies and may develop severe chronic anemia. Epidemiological studies done on Niterói population showed that B19 infection occurs periodically in late spring and summer. We report a study from 55 HIV infected patients atten...

Parvovirus B19 (B19) DNA was detected by dot blot hybridization in sera from 5 (17%) of 30 human immunodeficiency virus (HIV)-infected patients with hematocrits (HCT) of < or =24 and 4 (31%) of 13 HRV-infected patients with HCT of < or =20, suggesting that B19 is a reasonably common cause of severe anemia in HIV infection. The anemia promptly remitted after immunoglobulin therapy in 3 of 4 trea...

The childhood illness erythema infectiosum (EI) is caused by Parvovirus (PV) B19 with a slapped cheek-like rash and sometimes a lace-like rash on the extremities but cutaneous manifestions in infection in the adult can be atypical. A healthy 38-year-old male office worker and a 32-year-old non-pregnant female kindergarten teacher presented with fever (former; 37.2 C for 3 days, latter 38.1 C fo...

INTRODUCTION Human parvovirus B19 causes a wide range of complications in pregnant women including abortion, severe fetal anemia, non-immune hydrops fetalis, and even intrauterine fetal death. However, there is a dearth of information on the prevalence of the virus among pregnant women in southwestern Nigeria. METHODOLOGY Blood samples were collected from 231 pregnant women and screened for a...

This issue of Virulence features an article entitled “Human parvovirus B19 VP1u Protein as inflammatory mediators induces liver injury in na€ıve mice” which elucidated a relationship between expression of the Parvovirus B19 (B19) VP1unique region (VP1u) and liver damage in a transgenic mouse model. The in vivo effects of VP1u were investigated by subcutaneous injection of COS-7 cells transfecte...