The hypothesis that elimination of facultative and strict anaerobic microorganisms from the gastro-intestinal tract by antimicrobial drugs in the period of time around allogeneic bone marrow transplantation (BMT) prevents acute graft-versus-host disease (GVHD), was examined in a cohort of 112 children grafted between 1989 and 2002 for hematological malignancies. All patients received T-cell rep...

The structures of acetylcholine-binding protein (AChBP) and nicotinic acetylcholine receptor (nAChR) homology models have been used to interpret data from mutagenesis experiments at the nAChR. However, little is known about AChBP-derived structures as predictive tools. Molecular surface analysis of nAChR models has revealed a conserved cleft as the likely binding site for the 4/7 -conotoxins. H...

Metabolic adaptation of Saccharomyces cerevisiae cells from a nonfermentable carbon source to glucose induces selective, rapid breakdown of the gluconeogenetic key enzyme fructose-1,6-bisphosphatase (FBPase), a process called catabolite degradation. Herein, we identify eight novel GID genes required for proteasome-dependent catabolite degradation of FBPase. Four yeast proteins contain the CTLH ...

Abstract A dynamic nonlinear algebraic model with scale-similarity procedure (DNAM-SSD) is proposed for subgrid-scale (SGS) stress in large-eddy simulation of turbulence. The coefficients the DNAM-SSD are adaptively calculated through relation, which greatly simplifies conventional Germano-identity based (GID). a priori study shows that predicts SGS considerably better than velocity gradient (V...

This paper presents an audio genre detection framework that can be used for a multi-language audio corpus. Cepstral coefficients are considered and analyzed as the feature set for both a language dependent and language independent genre identification (GID) task. Language information is found to increase the overall detection accuracy on an average by at least 2.6% from its language independent...

Cells synthesize glucose if deprived of it, and destroy gluconeogenic enzymes upon return to glucose-replete conditions. We found that the Gid4 subunit of the ubiquitin ligase GID in the yeast Saccharomyces cerevisiae targeted the gluconeogenic enzymes Fbp1, Icl1, and Mdh2 for degradation. Gid4 recognized the N-terminal proline (Pro) residue and the ~5-residue-long adjacent sequence motifs. Pck...

The sheep nasal bot, Oestrus ovis (Diptera: Oestridae), is a cosmopolitan parasite commonly found in sheep and occasionally goats. Rarely a bot will migrate into the sheep brain (false gid). Following the complaint of an animal husbandman about high mortality rate in a sheep herd, the herd was clinically, hematologically, and pathologically examined exactly. Clinical, hematological, and patholo...

Road infrastructure has witnessed incremental changes in the past as compared to immense development by vehicle’s safety technology. Bott’s dots and other reflector devices are extensively used on road for lane separation improving edge detection. These come a large variety of shapes sizes, however, all them fall under category retroreflectivity since they depend vehicle lights provide reflecti...

This paper provides a modeling approach for average current control (ACC) operating in open-loop configuration. The converters chosen are non-ideal boost and synchronous continuous conduction mode (CCM). Initially, these mathematically modeled considering all the non-idealities using volt-sec amp-sec balance equations simulated MATLAB Simulink. transfer function of switch or inductor (Gid) to d...