نتایج جستجو برای: پژو 206
تعداد نتایج: 8956 فیلتر نتایج به سال:
miRNAs have been widely investigated in terms of cell proliferation and differentiation. However, little is known about their effects on bird growth. Here we characterized the promoter of miR-206 in chicken and found that the preferable promoter was located in 1200 bp upstream of pri-miR-206. In this region, many key transcription factors, including MyoD, c-Myb, CEBPα/β, AP-4, RAP1, Brn2, GATA-...
Glucose homeostasis is a complex indispensable process, and its dysregulation causes hyperglycemia and type 2 diabetes mellitus. Glucokinase (GK) takes a central role in these pathways and is thus rate limiting for glucose-stimulated insulin secretion (GSIS) from pancreatic islets. Several reports have described the transcriptional regulation of Gck mRNA, whereas its posttranscriptional mechani...
Colorectal cancer (CRC) is the most common cancer diagnosed worldwide, and the development of metastases is a major cause of mortality. Accumulating evidence suggests that microRNAs are important in carcinogenesis by affecting the expression of genes that regulate cancer progression. A number of studies have shown that miR-206 is frequently downregulated in many human malignancies, including CR...
یکی از مشکلات همیشگی در کارخانجات تولیدی، موجودی بیش از اندازه مورد نیاز، در انبارها و پای خط تولید است. این موجودی اضافی، باعث راکد ماندن سرمایه، از بین رفتن و معیوب شدن قطعات بر اثر انبارش طولانی مدت، هزینه های مازاد انبارداری و ... می شود. کارخانه ایران خودرو نیز مانند دیگر کارخانجات بزرگ تولیدی، با این معضل دست به گریبان بوده و در پی یافتن روشی برای کاهش سطح موجودی قطعاتش می باشد. سیستمهای ...
Lead isotopes and heavy metal concentrations were measured in two sediment cores sampled in estuaries of Xiangjiang and Lishui Rivers in Hunan province, China. The presence of anthropogenic contribution was observed in both sediments, especially in Xiangjiang sediment. In the Xiangjiang sediment, the lower (206)Pb/(207)Pb and higher (208)Pb/(206)Pb ratio, than natural Pb isotope signature (1.19...
BACKGROUND MicroRNAs (miRNAs) are a class of small non-coding RNAs that have been suggested to play an essential role in tumorigenesis. miR-206 functions as a tumor suppressor in several cancers. However, its role in non small cell lung cancer (NSCLC) remains unclear. METHODS Expression levels of miR-206 in NSCLC tissues and cell lines were determined by quantitative real-time PCR (qRT-PCR). ...
هدف اصلی این پژوهش بررسی تاثیر فرهنگ کار بر تکنیک های بهبود بهره وری بکار گرفته شده در دو شرکت تولیدی-صنعتی بنام :الف، شرکت تولیدی آذین که در زمینه تولید تجهیزات و تزئینات داخلی خودروهای پیکان ، پژو و پراید فعالیت می کند. ب، شرکت شتاب که در زمینه تولید قطعات موتوری خودروی پیکان و پژو 405 فعالیت می کند .
BACKGROUND Previous reports have shown a mutual negative feedback loop between microRNA (miR)-206 and estrogen receptor (ER) expression. Furthermore, decreased miR-206 expression in breast cancer (BC) is associated with the advanced clinical stage and lymph node metastasis. However, its role and the mechanism underlying the migration and invasion of ER positive BC remain unclear. RESULTS In t...
Growing evidence shows that microRNAs (miRNAs) regulate various developmental and homeostatic events in vertebrates and invertebrates. Osteoblast differentiation is a key step in proper skeletal development and acquisition of bone mass; however, the physiological role of non-coding small RNAs, especially miRNAs, in osteoblast differentiation remains elusive. Here, through comprehensive analysis...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by loss of motor neurons, denervation of target muscles, muscle atrophy, and paralysis. Understanding ALS pathogenesis may require a fuller understanding of the bidirectional signaling between motor neurons and skeletal muscle fibers at neuromuscular synapses. Here, we show that a key regulator of this signaling is...
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