Abstract Resident memory CD8 T cells (TRM) in the female reproductive tract (FRT) represent a primary defense mechanism against viruses. Presence of TRM mucosa is associated with accelerated viral control and rapid establishment an antiviral state. However, little known about factors that maintain this important barrier organ. Here, using single-cell RNA-sequencing (scRNA-seq) genetic methods, ...

BACKGROUND Thermogenic (TRM) supplements are often used by people seeking to decrease body weight. Many TRM supplements are formulated with multiple ingredients purported to increase energy expenditure and maximize fat loss. However, in the past some TRM ingredients have been deemed unsafe and removed from the market. Therefore, it is important to verify the safety of multi-ingredient TRM suppl...

In the internal dose evaluation, the specific absorbed fraction (SAF) and S-value are calculated from the reference phantom based on Caucasian data. The differences in height and weight between Caucasian and Asian may lead to inaccurate dose estimation. In this study, we developed the Taiwanese reference phantoms. 40 volunteers were recruited. Magnetic resonance images (MRI) were obtained, and ...

Videothermography (Video TRM), infrared beam thermography (IRTHRM), and contact thermography (Contact TRM) are utilized to detect asymmetries in temperatures between paired limbs. This information is controversially used in many diagnostic procedures in rehabilitation medicine. In this study, the effectiveness of the above techniques for scanning skin heat patterns and detecting asymmetries is ...

The Integrated Technical Reference Model (ITRM) provides guidelines and design principles for development of Wireless Sensor Networks (WSN). This paper describes an approach to implement a localization application for WSN using the I-TRM. It also provides a comparison between a typically organized WSN, the I-TRM and the Moteworks software platform.

BACKGROUND Pressure ulcers pose significant negative individual consequences and financial burden on the healthcare system. Prolonged sitting in High Fowler's position (HF) is common clinical practice for older adults who spend extended periods of time in bed. While HF aids in digestion and respiration, being placed in a HF may increase perceived discomfort and risk of pressure ulcers due to in...

The principal limitation of allogeneic hematopoietic stem cell transplantation except relapse remains the transplant-related mortality (TRM). In addition to graft-versus-host disease (GvHD), infections contribute to TRM in many patients. We describe herein a case of an adult patient presenting 5 months after haplo-identical transplantation an isolated fulminant hepatitis due to adenovirus.

The hypothesis was tested that amino acid substitutions in specific positions within human leukocyte antigen class I heavy chain would have different impacts on transplant-related mortality (TRM) in patients receiving transplanted bone marrow from unrelated donors. One hundred patients and their unrelated donors were typed by sequence-based typing for the human leukocyte antigen (HLA)-A, -B, an...

OBJECTIVES Acinetobacter baumannii is an important opportunistic pathogen and multidrug-resistant isolate. Although tigecycline is a potent antibiotic for treating infections with multidrug-resistant isolates, resistance is becoming a problem. This study aimed to explore the mechanism of tigecycline resistance in A. baumannii. METHODS A serial passage experiment was performed to collect isola...

OBJECTIVE TRM-484 is a novel drug consisting of nanoparticles of prednisolone with high affinity to chondroitin sulfate proteoglycans (CSPGs). This may allow for neointimal suppression via directed targeting to areas of injury at systemic concentrations low enough to avoid adverse side effects known to occur with oral delivery of steroids. METHODS AND RESULTS Atherosclerotic New Zealand white...