We investigated the dissemination of pathogenicity island (PAI) II(J96)-like elements (hra, hly, cnf1, and pap) among 455 Escherichia coli isolates from children and adults with urinary tract infection (UTI), neonates with meningitis or colonized healthy neonates, and 74 reference strains by means of PCR phylogenetic grouping, ribotyping, and PCR analysis of virulence genes. Colocalization of t...

We characterized 100 Escherichia coli urosepsis isolates from adult patients according to host compromise status by means of ribotyping, PCR phylogenetic grouping, and PCR detection of papG alleles and the virulence-related genes sfa/foc, fyuA, irp-2, aer, hly, cnf-1 and hra. We also tested these strains for copies of pap and hly and their direct physical linkage with other virulence genes in a...

Di(2-ethylhexyl)phthalate (DEHP), the plasticizer used in the biomedical production of blood storage bags, hemodialysis systems, cardiopulmonary bypass (CPB) circuitry, and intubation tubes, is extracted from the plastic material when it comes into contact with biological fluids and is converted to its principal metabolite, mono(2-ethylhexyl)phthalate (MEHP). We have shown that MEHP causes card...

IntroductionAmong the rare genetic causes of pulmonary alveolar proteinosis (PAP), some have been evidenced to be linked methionyl-tRNA synthetase (MARS) mutation. Lung transplantation (LTx) can offer in case secondary PAP, but it is admitted that underlying PAP should ruled out prevent recurrence disease. Nevertheless, recent investigations defective (MetRS) activity MARS-related and further, ...

Prostatic acid phosphatase (PAP) and ecto-5'-nucleotidase (NT5E) hydrolyze extracellular AMP to adenosine in dorsal root ganglia (DRG) neurons and in the dorsal spinal cord. Previously, we found that adenosine production was reduced, but not eliminated, in Pap⁻/⁻/Nt5e⁻/⁻ double knock-out (dKO) mice, suggesting that a third AMP ectonucleotidase was present in these tissues. Here, we found that t...

Throughout the past thirty years, the perception of cervical carcinoma has shifted from that of a mysteriously fatal disease, to one of the sexually transmitted, human papillomavirus (HPV) related infection. HPV DNA has been found in almost all cervical invasive and preinvasive cervical neoplasms. Conventional Pap smear, which was established in the early sixties reduced effectively the morbidi...

A bstract . This pap er concern s the study of some mathemati cal proper t ies of Thermodyn amic Au tomata . In the pr esen t pap er , t he govern ing lineari zed differenti al equat ionsfor which a rigorous trea tment is po ssibl eare studied . The driving terms are assumed period ic and t he controls are assumed piecewise const ant . T he explicit solut ion is found in the most general case w...