نتایج جستجو برای: ژن qnra
تعداد نتایج: 15967 فیلتر نتایج به سال:
conclusions the most common qnr gene was qnrb, and none of the isolates carried qnra or qepa. the aac (6’)-ib-cr variant was the most prevalent pmqr gene, and it was associated with the prevalence of ciprofloxacin resistance in our esbl-producing isolates. results of the 123 isolates, 103 (83.73%) had one of the five pmqr genes, including 83 (83.83%) of the 99 e. coli strains and 20 (86.95%) of...
conclusions the high prevalence of quinolone resistance genes, which indicates antibiotic resistance, in the imam reza hospital of mashhad is a major concern. hence, the antibiotics prescription policy should be revised, and infection control measures should be improved. results eighty-six (43%) isolates were ciprofloxacin-resistant. the pct identified 85 (42.5%) of 200 e. coli isolates as esbl...
ABSTRACT Background and Objective: Klebsiella pneumoniae is one of the most common causes of bacterial infections. Presence of plasmid-mediated quinolone resistance genes causes low level of resistance in K. pneumoniae. This study investigated the prevalence of resistance to quinolones and fluoroquinolones, and the frequency of qnrA, qnrB and qnrS genes amo...
Avian pathogenic Escherichia coli (APEC) are the major cause of colibacillosis in poultry production. In this study, a total of 22 E. coli isolated from colibacillosis field cases and 10 avian faecal E. coli (AFEC) were analysed. All strains were characterised phenotypically by susceptibility testing and molecular typing methods such as pulsed-field gel electrophoresis (PFGE) and multi-locus se...
The prevalence of three plasmid-mediated quinolone resistance determinants, QnrA, QnrB, and QnrS, among 526 nonreplicate clinical isolates of Enterobacter cloacae collected at a Taiwanese university hospital in 2004 was determined by PCR and colony hybridization, and the association of Qnr with the IMP-8 metallo-beta-lactamase was investigated. Eighty-six (16.3%) of all isolates were qnr positi...
OBJECTIVES To determine the genetic location and environment of the qnrA6 gene in Proteus mirabilis PS16 where it was first described and to characterize the quinolone resistance qnrA6 confers. METHODS Transformation experiments and Southern blotting were performed for plasmid and genomic DNA of P. mirabilis PS16 to determine the qnrA6 location. Combinatorial PCRs with primers in qnrA6 and ge...
To the Editor: The emergence of plasmid-mediated, and thus transfer-able, quinolone resistance determinants has been recently discovered (1) and shown to involve the pentapeptide repeat protein Qnr, which interacts with DNA gyrase and topoisomerase IV to prevent quinolone inhibition (2,3). Qnr determinants confer resistance to nalidixic acid and reduced susceptibility to fl uoroquinolones (3). ...
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