BACKGROUND The mechanism of a high-fat, low-carbohydrate ketogenic diet (KD) in alleviating drug-resistant epilepsy is unknown but may be related to systemic ketosis induced under this treatment. The need for frequent measurement of systemic ketosis, which is essential for improving maintenance of the KD in patients and for studying mechanism of the KD action, has prompted us to validate the br...

Introduction Diabetes mellitus till recently has beeen divided into two main types-the 'juvenile' and 'maturity onset'-on the basis of the age at onset, bodyweight, susceptibility to ketosis and response to insulin and oral therapy. Lawrence (1951) described a rare variety of lipo-atrophic diabetes characterized by earlier age of onset, loss of subcutaneous fat, rarity of ketosis and high insul...

Research of the frequency increased ketone bodies in cows during transition period three weeks before calving and after should determine tendency Holstein breed to ketosis. It is also important investigate relationship between changes blood biochemical parameters development treatment The purpose study was effectiveness using a probiotic strain bacteria subclinical ketosis drying off calving. f...

Nutritional ketosis may enhance cerebral energy metabolism and has received increased interest as a way to improve or preserve performance and resilience. Most studies to date have focused on metabolic or neurological disorders while anecdotal evidence suggests that ketosis may enhance performance in the absence of underlying dysfunction. Moreover, decreased availability of glucose in the brain...

The cerebral metabolic activity of glucose and ketones was compared in ketotic rats with insulin-dependent diabetes mellitus (IDDM) and in normal controls. In the IDDM rats, ketosis had been present < 12 hours and the diabetes was of recent onset. After sufficient infusion of labeled [1-13C]glucose to achieve steady-state levels, the ratio of the fractional enrichment of the metabolites [4-13C]...

A 2-year-old boy was admitted with diagnosis of diabetes debut, with blood glucose of 500 mg% on admission, without ketosis or metabolic acidosis. He also presented bilious vomiting and brownish bloody stools. He was operated with a presumptive diagnosis of acute intestinal obstruction. The final diagnosis was volvulus, secondary to congenital malrotation. After surgery, he normalized blood sug...

We present the clinical case of a patient who was admitted with an onset of diabetes mellitus (DM) with associated ketosis and whose clinical, hormonal, and radiological evolution revealed the presence of primary hyperparathyroidism, pancreatic neuroendocrine tumor, and GH-producing pituitary macroadenoma in the context of multiple endocrine neoplasia type 1 (MEN1). DM is relatively common in c...

Mammary uptakes of glucose and long-chain fatty acids are proposed to be the major metabolic determinants of milk volume production and mammary efficiency, respectively. Moreover, the ratio of glucogenic to lipogenic nutrients in the diet is proposed to be the major determinant of spontaneous ketosis. Experimental evidence and clinical observations are adduced in support of these three interrel...