A Raptor code is a concatenation of a fixed rate precode and a Luby-Transform (LT) code that can be used as a rateless error-correcting code over communication channels. By definition, Raptor codes are characterized by irregularity features such as dynamic rate, check-degree variability, and joint coding, which make the design of hardware-efficient decoders a challenging task. In this paper, se...

Intestinal cell kinase (ICK), originally cloned from the intestine and expressed in the intestinal crypt epithelium, is a highly conserved serine/threonine protein kinase that is similar to mitogen-activated protein kinases (MAPKs) in the catalytic domain and requires dual phosphorylation within a MAPK-like TDY motif for full activation. Despite these similarities to MAPKs, the biological funct...

In this work we address reliable file delivery over mobile broadcast networks using Raptor Codes. We assume a point-to-multipoint (broadcast) transmission, where original source symbols are protected by additional parity symbols. Despite the good performance of Raptor codes, as specified for Multimedia Broadcast/Multicast Services (MBMS) within 3GPP, reliable delivery cannot be guaranteed due t...

A classic metabolic concept posits that insulin promotes energy storage and adipose expansion, while catecholamines stimulate release of adipose energy stores by hydrolysis of triglycerides through β-adrenergic receptor (βARs) and protein kinase A (PKA) signaling. Here, we have shown that a key hub in the insulin signaling pathway, activation of p70 ribosomal S6 kinase (S6K1) through mTORC1, is...

BACKGROUND mTOR, which can form mTOR Complex 1 (mTORC1) or mTOR Complex 2 (mTORC2) depending on its binding partners, is frequently deregulated in the pulmonary neoplastic conditions and interstitial lung diseases of the patients treated with rapalogs. In this study, we investigated the relationship between mTOR signaling and epithelial mesenchymal transition (EMT) by dissecting mTOR pathways. ...

Acute alcohol intoxication decreases skeletal muscle protein synthesis by impairing mammalian target of rapamycin (mTOR). In 2 studies, we determined whether inhibition of branched-chain amino acid (BCAA) catabolism ameliorates the inhibitory effect of alcohol on muscle protein synthesis by raising the plasma BCAA concentrations and/or by improving the anabolic response to insulin-like growth f...

In this technical report we present RAPTOR (Rapid Three-Dimensional Orientation Resolver), which is a novel pipeline for inferring solely from 2D image data the 3D position and orientation (pose) of known classes of rigid objects for which man-made 3D models are available. There are many existing systems and techniques that attempt to infer 3D meshes and scene information from 2D image or video...

mTOR is an evolutionarily conserved kinase that plays a critical role in sensing and responding to environmental determinants. Recent studies have shown that fine-tuning of the activity of mTOR complexes contributes to organogenesis and tumorigenesis. Although rapamycin, an allosteric mTOR inhibitor, is an effective immunosuppressant, the precise roles of mTOR complexes in early T-cell developm...

Biodiversity conservation on private land of the developed world faces several challenges. The costs of land are often high, and the attitudes of landowners towards conservation are variable. Scientists and practitioners need to scan for and adopt cost-effective solutions that allow for the long-term sustainability of conservation measures on private land. In this study, we focus on one of such...

Ransomware, a type of malicious software that encrypts a victim’s files and only releases the cryptographic key once a ransom is paid, has emerged as a potentially devastating class of cybercrimes in the past few years. In this paper, we present RAPTOR, a promising line of defense against ransomware attacks. RAPTOR fingerprints attackers’ operations to forecast ransomware activity. More specifi...