نتایج جستجو برای: کشورهای oic
تعداد نتایج: 27362 فیلتر نتایج به سال:
3alpha-Hydroxy-5 beta-cholan-24-oic (lithocholic) acid is a relatively minor component of hepatic bile acids in humans but is highly cytotoxic. Hepatic microsomal oxidation offers a potential mechanism for effective detoxification and elimination of bile acids. The aim of the present study was to investigate the biotransformation of lithocholic acid by human hepatic microsomes and to assess the...
The methanol extract of Brazilian propolis was fractionated by HPLC, based on HuH13 (human hepatocellular carcinoma) cell cytotoxicity assay. Two isomers of diterpenoid with a molecular formula of C20H30O3 (MW: 318.46) were isolated. The structures of these colorless compounds were determined as clerodane diterpenoids (I, 15-oxo-3, 13Z-kolavadien-17-oic acid; II, 15-oxo-3Z, 13E-kolavadien-17-oi...
تاریخ دریافت: 6/12/86 تاریخ پذیرش: 19/12/86 نظریه های جدید در عرصه تجارت بین المللی بر این نکته تأکید دارند که افزایش شدت تجارت بین کشورها و حرکت به سمت یکپارچگی تجاری، بر همزمانی چرخه های تجاری آنها تأثیرگذار است. هدف اصلی مقاله حاضر، ارزیابی عمده عوامل مؤثر بر همزمانی چرخه های تجاری کشورهای اسلامی با تأکید بر شاخص یکپارچگی تجاری است که با استفاده از یک سیستم همزمان در طی مقطع زمانی 2005- 19...
در این پژوهش از میان عوامل و متغیرهای گوناکون که بر رشد اقتصادی تاثیر گذار هستند، دو متغیر سرمایه اجتماعی و هزینه های بهداشتی مورد بررسی قرار گرفته است. در پژوهش حاضر سعی شده است تا با اتخاذ رویکرد اقتصاد سنجی بیزینی و به کارگیری روش میانگینگیری مدل بیزینی(bma) اثر دو متغیر مذکور را بر رشد اقتصادی 33 کشور منتخب عضو سازمان کنفرانس اسلامی(oic) مطالعه و بررسی شود. با استناد به نتایج این مطالعه ...
The first electrophilic α-amination reaction of labdane-type diterpene (−)-(5S,9S,10S,13S)-labd-7-en-15-oic acid and (+)-(5S,8R,9R,10S,13R)-8-hydroxylabdan-15-oic acid, isolated from aerial parts Ageratina jocotepecana is presented. In the presence dibenzylazodicarboxylate proline followed by an in situ reduction, corresponding hydrazino alcohols were obtained. It demonstrated that moiety had n...
An overview of the synthetic methods developed to build all the cis-fused stereoisomers of octahydroindole-2-carboxylic acid (Oic) and its -methylated derivative [( Me)Oic] in enantiomerically pure form is presented. Both asymmetric synthetic strategies (auxiliaryor substrate-controlled processes) and procedures based on the resolution of racemic compounds (chemical, enzymatic, and chromatograp...
Three new ursane-type triterpenoids, 3α,6α,30-trihydroxy-ursan-28-oic acid (1), 3α,30-dihydroxy-6-oxo-ursan-28-oic acid (2) and 3α,6α,7α,30-tetrahydroxy-ursan-28-oic acid (3), together with one known triterpenoid, betulinic acid (4), one known anthraquinone, 1,7-dihydroxy-2-methylanthraquinone (5), four known phenols, 1,3,5-trimethoxybenzene (6), p-hydroxybenzoic acid (7), syringic acid (8), is...
In this study, three semisynthetic betulonic acid-based compounds, 20(29)-dihydrolup-2-en[2,3-d]isoxazol-28-oic acid, 1-betulonoylpyrrolidine, and lupa-2,20(29)-dieno[2,3-b]pyrazin-28-oic acid, were studied in biotransformation experiments using Nicotiana tabacum and Catharanthus roseus cell suspension cultures. Biotransformation was performed using cyclodextrin to aid dissolving poorly water-s...
Two new triterpenoids, 30-O-beta-D-glucopyranosyloxy-2alpha,3alpha,24-trihydroxyurs-12,18-diene-28-oic acid O-beta-D-glucopyranosyl ester (1) and 2alpha,3beta,3,30-tetrahydroxyurs-12,18-diene-28-oic acid O-beta-D-glucopyranosyl ester (2) were isolated from roots of Actinidia valvata Dunn. Their structures were elucidated by means of extensive spectroscopic studies. Both these two new compounds ...
Three new lanostanoid triterpenes--ganotropic acid (1), 3β,7β,15α,24-tetra- hydroxy-11,23-dioxo-lanost-8-en-26-oic acid (2) and 3β,7β,15α,28-tetrahydroxy-11,23- dioxo-lanost-8,16-dien-26-oic acid (3)--were isolated from the n-BuOH extract of the fruiting bodies of the mushroom Ganoderma tropicum. Their structures were elucidated by 1D and 2D NMR spectroscopy, as well as HR-EI-MS data.
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