The self-renewal characteristics of stem cells render them vital engines of development. To better understand the molecular mechanisms that determine the properties of stem cells, transcript profiling was conducted on quiescent center (QC) cells from the Arabidopsis thaliana root meristem. The AGAMOUS-LIKE 42 (AGL42) gene, which encodes a MADS box transcription factor whose expression is enrich...

130. A Prospective Cohort Study Evaluating the Impact of the Multiplex Respiratory Virus Panel (MRVP) PCR Test on the Clinical Management of Suspected Respiratory Viral Infections in Adult Patients at the McGill University Health Centre (MUHC) Colin Yee, MD, MSc; Nandini Dendukuri, PhD; Ioana Nicolau, MSc; Alison Sinclair, MD, PhD; Makeda Semret, MD; Charles Frenette, MD; Internal Medicine, McG...

Department of Biochemistry, Université de Montréal, Montréal QC H3C 3J7 (W.R., R.S., J.D., A.A., E.H., S.M.), Institute of Research in Immunology and in Cancerology, Université de Montréal, Montréal QC H3C 3J7 (W.R., J.D., E.H., S.M.), Montreal Center for Experimental Therapeutics in Cancer, Jewish General Hospital, Montreal QC H3T 1E2 (W.R., J.D., E.H., J.H.W., S.M.), Department of Physiology,...

Meningococcal Disease (IMD-B) Incidence and Outcomes in the Province of Quebec, Canada Bruce Tapiero, MD; Léna Coic, MD; Philippe Ovetchkine, MD MSc; Philippe De Wals, MD, PHD; Jean Baptiste Le Meur, MSc; Adela Barbaros, MD; Brigitte Lefebvre, PhD; Department of Pediatrics, Division of Infectious Diseases, CHU Sainte-Justine – University of Montreal, Montreal, QC, Canada; Laval University, Queb...

MARIE-CLAUDE TREMBLAY1,2* and LUCIE RICHARD1,2,3,4,5* École de santé publique, Université de Montréal, Montreal, QC, Canada IRSPUM (Institut de recherche en santé publique de l’Université de Montréal), Montreal, QC, Canada Faculty of Nursing, Université de Montréal, Pavillon Marguerite d’Youville, bur. 5104, 2375 ch. de la Côte Ste-Catherine, Montreal, QC, Canada H3T 1A8 Léa-Roback Research Cen...

Death Receptor 5 (DR5) is known to be an important anti-cancer drug target. TRAIL is a natural ligand of DR5, but its drug action is limited because of several factors. A few agonistic ligands were identified as TRAIL-DR5 axis modulators, which enhance the cellular apoptosis. Literature suggest that quinacrine (QC) acts as a DR5 agonistic ligand. However, the detailed mechanism explaining how Q...

PURPOSE The purpose of our investigation was to evaluate the response and minimal residual disease by quantitative competitive PCR (QC-PCR) studies in patients with chronic myeloid leukemia (CML) treated with imatinib mesylate. EXPERIMENTAL DESIGN One hundred eighty patients with Philadelphia chromosome (Ph)-positive chronic-phase CML after IFN-alpha failure, treated with imatinib mesylate, h...

BACKGROUND Intra-abdominal packing with laparotomy pads (LP) is a common and rapid method for hemorrhage control in critically injured patients. Combat Gauze™ and Trauma Pads™ ([QC] Z-Medica QuikClot®) are kaolin impregnated hemostatic agents, that in addition to LP, may improve hemorrhage control. While QC packing has been effective in a swine liver injury model, QC remains unstudied for human...

Let T (QC) (resp. T ) be the C∗-algebra generated by the Toeplitz operators {Tφ : φ ∈ QC} (resp. {Tφ : φ ∈ L∞}) on the Hardy space H2 of the unit circle. A well-known theorem of Davidson asserts that T (QC) is the essential commutant of T . We show that the essential commutant of T (QC) is strictly larger than T . Thus the image of T in the Calkin algebra does not satisfy the double commutant r...

A major neuropathological hallmark of Alzheimer's disease (AD) is the deposition of aggregated β amyloid (Aβ) peptide in the senile plaques. Aβ is a peptide of 38-43 amino acids and its accumulation and aggregation plays a key role early in the disease. A large fraction of β amyloid is N-terminally truncated rendering a glutamine that can subsequently be cyclized into pyroglutamate (pE). This m...