This work presents a new access method (LES-tree) for spatio-temporal databases that handles discrete change events over objects’ spatial attributes. The main characteristic of this structure is that, in addition to the traditional database snapshots, LEStree explicitly stores the events in log structures associated with space partitions. The definition of this new access method aims to extend ...

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Following the success of single agent CTLA-4 and PD-1 inhibition, focus has shifted to the study of novel combinations of immune therapeutics with the goal of improving efficacy. A major breakthrough was seen in CheckMate 067 as dual PD1/CTLA4 blockade demonstrated robust and often durable responses. However, this efficacy came at the cost of considerable toxicity, as ≥ 50% of patients on combi...

Homolateral Extremity Synkinesia after the Stroke Huseyin Buyukgol1*, Muzaffer Gunes2 and Fatma Aysen Eren2 1KTO Karatay University, Medicana Faculty of Medicine, Department of Neurology. Konya/Turkey 2Aksaray Training and Research Hospital. Department of Neurology. Aksaray/Turkey *Address for Correspondence: Huseyin Buyukgol, KTO Karatay University, Medicana Faculty of Medicine, Department of ...

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The article aims to evaluate the level of analytical part CRM in SMEs Czechia and its impact on increasing companies’ profitability. In empirical part, primary quantitative research was carried out. subject selected for activities. object Moravian-Silesian Region. questionnaire survey attended by 1 067 respondents. To utilisation activities, PDCA method (Deming cycle), which is used proce...

En México, el maíz (Zea mays L), es cultivo alimenticio más importante. A pesar de que su contenido proteínico (11 %) y sus proporciones los aminoácidos esenciales lisina triptofano son bajos (0.29 .067 % respectivamente), en promedio proporciona 39 la proteína asimilable 59 energía ingieren mexicanos. El consumo anual aparente 209.8 kilogramos por persona (Morris López, 2000). región tropical ...