نتایج جستجو برای: 1 selective alzheimer disease indicator

تعداد نتایج: 4080814  

2009
Jerzy Leszek Irena Dobrzanska

Alzheimer's Disease (A.D.) is a multifarious, complex syndrome, which probably comprises different etiopathogenic subunits. Work by several authors has shown immunological disturbances in A.D. underlining the importance of immunological imbalance in the explanation of the etiopathogenesis and progress of some forms of A.D. An early diagnosis of A.D. is important because changes in central nervo...

Introduction: Effects of many flavonoids have been studied on memory, learning and improvement of Alzheimer. Many flavonoids are effective in the improvement of Alzheimer. Since no study has been conducted on the effect of salvigenin on memory and learning, our aim was to examine the effect of this flavonoid. Methods: Intraperitoneal injection of D-galactose at a dose of 120 mg / kg was used f...

2012
Juliane Proft Norbert Weiss

To date, nearly 35.6 million people world wide live with dementia, and the situation is going to get worse by 2050 with 115.4 million cases.(1) In the western world, the prevalence for dementia in people over the age of 60 is greater than 5% and two thirds are due to Alzheimer disease,(2) (-) (5) the most common form of dementias.   Alzheimer disease (AD), first described as "presenile dementi...

Journal: :Brain : a journal of neurology 2015
Stephanie J B Vos Frans Verhey Lutz Frölich Johannes Kornhuber Jens Wiltfang Wolfgang Maier Oliver Peters Eckart Rüther Flavio Nobili Silvia Morbelli Giovanni B Frisoni Alexander Drzezga Mira Didic Bart N M van Berckel Andrew Simmons Hilkka Soininen Iwona Kłoszewska Patrizia Mecocci Magda Tsolaki Bruno Vellas Simon Lovestone Cristina Muscio Sanna-Kaisa Herukka Eric Salmon Christine Bastin Anders Wallin Arto Nordlund Alexandre de Mendonça Dina Silva Isabel Santana Raquel Lemos Sebastiaan Engelborghs Stefan Van der Mussele Yvonne Freund-Levi Åsa K Wallin Harald Hampel Wiesje van der Flier Philip Scheltens Pieter Jelle Visser

Three sets of research criteria are available for diagnosis of Alzheimer's disease in subjects with mild cognitive impairment: the International Working Group-1, International Working Group-2, and National Institute of Aging-Alzheimer Association criteria. We compared the prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage according to these criteria. Subjects...

Journal: :Annals of internal medicine 2001
T W Chow C H MacLean

Dementia is defined by acquired, progressive impairment in two or more cognitive areas (for example, frontal executive function, mood, or memory) that is severe enough to render a person dependent on others. Dementia is a leading cause of disability among older adult patients; Alzheimer disease is the most common etiology. The prevalence of Alzheimer disease is approximately 2% among persons 60...

Journal: :AJNR. American journal of neuroradiology 2015
T P Hansen J Cain O Thomas A Jackson

BACKGROUND AND PURPOSE Dilated perivascular spaces have been shown to be a specific biomarker of cerebral small-vessel disease in young patients with dementia. Our aim was to examine the discriminative power of dilated cerebral perivascular spaces as biomarkers of small-vessel disease in a very elderly population of patients with dementia. MATERIALS AND METHODS We studied healthy volunteers (...

Borhani, Tahura Sadat , Fayyaz-Movaghar, Afshin , Kamel-Mirmostafaee, Mohammad Taghi ,

Background and Purpose: The identification of genetics risk factors of human diseases is very important. This study is conducted to model the allele frequencies (AFs) of Alzheimer’s disease. Materials and Methods: In this study, several candidate probability distributions are fitted on a data set of Alzheimer’s disease genetic risk factor. Unknown parameters of the considered dis...

Hosein Hamadiyan, Mitra Rooin Peikar, Sepehr Rasekhi,

Patients with Type 1 diabetes mellitus have a high prevalence of coeliac disease, symptoms of which are often mild, atypical, or absent. Untreated coeliac disease is associated with an increased risk of malignancy, particularly of lymphoma. Therefore, we report a 9-year-old girl with Coeliac disease, diabetes type 1 and Selective IgA deficiency. A 9-year-old female patient presented in august 2...

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