We determine all the non-abelian normal CM-fields of degree 24 with class number one, provided that the Galois group of their maximal real subfields is isomorphic to A4, the alternating group of degree 4 and order 12. There are two such fields with Galois group A4 × C2 (see Theorem 14) and at most one with Galois group SL2(F3) (see Theorem 18); if the Generalized Riemann Hypothesis is true, the...

Stimulated by Ma’s idea which explains the tribimaximal neutrino mixing by assuming an A4 flavor symmetry, a lepton mass matrix model is investigated. A Frogatt-Nielsen type model is assumed, and the flavor structures of the masses and mixing are caused by the VEVs of SU(2)L-singlet scalars φ u i and φ i (i = 1, 2, 3), which are assigned to 3 and (1,1,1) of A4, respectively.

Stimulated by Ma’s idea which explains the tribimaximal neutrino mixing by assuming an A4 flavor symmetry, a lepton mass matrix model is investigated. A Frogatt-Nielsen type model is assumed, and the flavor structures of the masses and mixing are caused by the VEVs of SU(2)L-singlet scalars φ u i and φ i (i = 1, 2, 3), which are assigned to 3 and (1,1,1) of A4, respectively.

AS-3-Ketosteroid isomerase of Pseudomonas testosteroni is a homogeneous and crystalline enzyme that promotes the irreversible conversion of A5-3-ketosteroids to A4-3-ketosteroids (1, 2). This enzyme is one of the most active catalytic proteins known, since each mole (molecular weight 40,800) converts 16.7 x lo6 moles of A5-androstene-3, 17-dione (I) to A4-androstene-3, 17dione (II) per minute a...

Many strains of zygomycetes and actinomycetes were found to convert milbemycin A4 (1a) to 13 beta-hydroxymilbemycin A4 (1b). Among these strains, Cunninghamella echinulata ATCC 9244 had the most efficient 13 beta-hydroxylation ability on milbemycins. In the conversion of milbemycin A3 (2a), 29-hydroxymilbemycin A4 (4a), and 30-hydroxymilbemycin A4 (5a) with this strain, only 13 beta-hydroxylate...

Hepatic fibrosis may ultimately result in organ failure and death, a reality compounded by the fact that most drugs for liver fibrosis appear to be effective only if given as a prophylactic or early treatment. In a dimethylnitrosamine-induced liver fibrotic model, aspartate aminotransferase/alanine aminotransferase levels could not precisely distinguish the differences between the initial stage...

Ephrin-A4 is a ligand for the erythropoietin-producing hepatocellular (Eph) receptor family of tyrosine kinases. We have identified a secreted form of ephrin-A4, denoted ephrin-A4 (s), which is encoded by an alternatively spliced mRNA and is produced by in vivo activated B cells in tonsils. Blood B cells secrete ephrin-A4 (s) upon stimulation via the B-cell antigen receptor. A subpopulation of ...

introduction and aim: arsenic is a metalloid toxic for plants. arsenic is polluting the environment through the natural and artificial resources. it is harmful to human health. arsenic in plants for the production of the reactive oxygen species (ros) lead to destruction of nucleic acids and proteins in tissues of plants. it also reduces of photosynthesis and growth by destroy of the membranes o...

The bifunctional leukotriene A4 hydrolase catalyzes the final step in the biosynthesis of the proinflammatory leukotriene B4. During exposure to the substrate leukotriene A4, a labile allylic epoxide, the enzyme is gradually inactivated as a consequence of the covalent binding of leukotriene A4 to the active site. This phenomenon, commonly referred to as suicide inactivation, has previously bee...