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امروزه بزرگترین مانع بر سر راه صنعتی شدن تولید آراشیدونیک اسید هزینه ی بالای عملیات آن و یکی از عوامل افزایش هزینه، قیمت مواد خام اولیه است. در این تحقیق از قارچ مورتیرلا آلپینا cbs754.68 برای تولید آراشیدونیک اسید استفاده شد. در ابتدا از ضایعاتی همچون خرمای درجه سه، آب پنیر، آب پنیر بدون افزودن منبع نیتروژنی و ملاس برای تولید آراشیدونیک اسید استفاده شد، تا از بین آن ها بهترین سوبسترا انتخاب شو...
Abstract Background and Aims The management of angiotensin-converting enzyme inhibitor (ACEI) angiotensin receptor blocker (ARB) in patients with ongoing acute kidney injury (AKI) during hospitalization is debated. This study aimed to explore whether the use ACEI or ARB (ACEI/ARB) an AKI episode associated adverse clinical outcomes. Method nationwide, retrospective cohort included 10,559 aged 1...
RATIONALE Choice and intensity of early (first 48 h) sedation may affect short- and long-term outcome. OBJECTIVES To investigate the relationships between early sedation and time to extubation, delirium, and hospital and 180-day mortality among ventilated critically ill patients in the intensive care unit (ICU). METHODS Multicenter (25 Australia and New Zealand hospitals) prospective longit...
AIMS We aimed to characterize abnormal liver function tests in patients with heart failure (HF), as they are commonly encountered yet poorly defined. METHODS AND RESULTS We used data from ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure) to characterize associations with baseline liver function tests (LFTs). Each LFT was analysed as both a continuo...
INTRODUCTION This study investigated the effects of recurrent urinary tract infections (rUTI) and the impact of prophylaxis on rUTI and patients' quality of life (QoL). METHODS Altogether, 575 patients affected by rUTI were included in a 6-month observational study. QoL was assessed using the Hospital Anxiety and Depression (HAD) and the Leicester scales. Statistical analyses were performed u...
It is well recognized that masticatory muscle function helps determine morphology, although the extent of function on final form is still debated. GDF-8 (myostatin), a transcription factor is a negative regulator of skeletal muscle growth. A recent study has shown that mice homozygous for the myostatin mutation had increased muscle mass and craniofacial dysmorphology in adulthood. However, it i...
Denoting by (rn)n≥1 the increasing sequence of the numbers p with p prime and α ≥ 2 integer, we prove that rn+1 − 2rn + rn−1 is positive for infinitely many values of n and negative also for infinitely many values of n. We prove similar properties for r n−rn−1rn+1 and 1 rn−1 − 2 rn + 1 rn+1 as well.
UNLABELLED Many techniques were applied to treat patients with sulcus vocalis and scarred vocal folds. Their results were not good enough. In the Technique of Vocal Fold Pediculated Mucosa Flap, an anterior pediculated flap of vocal fold is positioned on the superficial layer of the lamina propria, below the free margin. AIM To describe histological postoperative findings on the superficial l...
Methods This is an observational prospective cohort study. Population is composed of adults hospitalized in ICU of the Service of Burns near University Hospital Center, Tirana, Albania for 5 years(2010-2015).Patients are grouped according glucose values on three categories: Patients with Euglycemia ( 80-120 mg/dL), Moderate Hyperglycemia (121-180 mg/dL) and Critical Hyperglycemia (> 180 mg/dL )...
BACKGROUND New biomarkers are needed to assess the severity of necrotizing soft tissue infection (NSTI) at an early stage and to individualize treatment strategies. We assessed pentraxin-3 (PTX3) as a marker of disease severity and risk of death in patients with NSTI. METHODS We conducted a prospective, observational study in the intensive care unit at Copenhagen University Hospital, where tr...
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