a series of n-substituted-2,4-thiazolidinedione derivatives (tzds) were prepared via n-alkylation of 2,4-tzd at position 3 using substituted benzyl halides. synthesized n-substituted-2,4-tzd was then substituted at position 5 with substituted aromatic aldehyde according to knoevenagel condensation method. structures of the compounds were elucidated using various spectral techniques viz. ir, 1hn...

The aim of this study was to characterize the phytochemicals and investigate antimicrobial efficacy shade dried roots Asparagus adscendens. powder were extracted with chloroform after removal solvent under reduced pressure subjected for chromatographic separation. After column chromatography purification five compounds i.e .hexacosanyltriacontanoate, hexatriacontanone, 2,3,5,7-tetramethoxydi hy...

Coumarin derivatives have shown different biological activities, such as antifungal, antibacterial antiinflammatory, and antioxidant besides antibiotic resistance modulating effects, anti-HIV, hepatoprotective, antitumor effect. So, new coumarin (hydrazones an amide) were synthesized through multisteps reactions. All the target compounds characterized by FT-IR spectroscopy, 1HNMR analysis. The ...

New N-substituted ?-aminonitrile derivatives from menthol were synthesized by consecutive succinic ester formation, propargylation, 1,3-dipolar Huisgen cycloaddition and Strecker reaction. The structures of the compounds confirmed diverse spectroscopic techniques including 1HNMR, 13C-NMR, ESI-MS IR. novel evaluated for their in vitro antibacterial activities against Staphylococcus aureus as Gra...

The research included the preparation of two Schiff bases MA1,2 starting from1-methyl-pyrazole-4-carbaldehyde with 4-chloroaniline or 4-amino antipyrine in equal moles presence glacial acetic acid. Then xazepane rings MA (3-6) were prepared from phthalic anhydride maleic anhydride. chemical formulas confirmed using FTIR, 1HNMR, and 13CNMR spectroscopy. toxicity activity compound MA2 against bre...

Through this study, a group of heterocyclic compounds represented by five-membered ring, seven rings, and tetracyclic Oxazepine, β-lactam, Thiazolidines, Imidazolidines, were prepared depending on the intermediate compound, Schiff bases, that from reaction 2-Aminobenzimidazol with 4-Bromobenzaldehyde to form (azomethine-CH=N) above formed pathway bond. All new derivatives created Fourier Transf...