Abstract Introduction The genotypes HLA DR3/DR4, DR3/DR3, DR4/DR4 are associated with a predisposition to diabetes. This study evaluated UK recipient outcomes after pancreas transplantation from donors diabetes-associated genotypes. Methods Data on all transplants 2004–2019 was obtained the NHSBT-UK Registry, n=2,938. HLA-DR type recorded for organ donors. Re-transplants and those missing patie...

Background: South America has the largest area of temperate forests in Southern Hemisphere, which grow diverse site conditions. The aim this paper is to review practices silviculture applied and recommended for these forests, discuss prospects develop new silvicultural proposals improve sustainability, adaptation in-situ conservation forest ecosystems. Methods: We reviewed knowledge four major ...

Introduction Auditory Hallucination(AH) is a core & one of the most common symptom seen in schizophrenia. A prevalence study found that 1yr AHs 70% among patients Most theories discuss biological psychological factors phenomenology voices. There definitely role neuroanatomical basis for occurrence psychotic phenomenon AHs, however environment sociocultural background play important their ge...

Abstract Background Treatment of secondary hydrocephalus due to posterior fossa tumors in these children is still a matter controversy, although preoperative ventriculo-peritoneal shunt (VP shunt) insertion before tumor excision widely accepted among neurosurgeons but many attempts are rising minimize permanent VP and associated complications introducing third endoscopic ventriculostomy (ETV) a...

Cardiac resynchronization therapy (CRT) is an important therapeutic option in selected pediatric and congenital heart disease (CHD) patients with reduced systemic ventricular (SV) ejection fraction (EF). However, the identification of optimal responders challenging. This highly pertinent context increased technicalities CRT implant procedures compared to adults structurally normal hearts. To id...

Shiitake mushroom, the common Japanese name for Lentinus edodes (Fig. 1), derives from the mushroom associated with the shii tree (Castanopsis cuspidate Schottky) and take, the Japanese word for mushroom (Table 1). Because Japan is the world leader in production of this type of mushroom, the mushroom is now widely known by this name. These mushrooms are renowned in Far East countries (e.g., Jap...

A current paradigm in conservation biology is that forest harvest practices that better approximate natural disturbance processes are more likely to conserve biodiversity. We contrasted bird communities in three replicate stands in each of 1, 13–15, and 22–28 yr old forests following wildfire and harvest in north-central Alberta, Canada. Stands were chosen from old (.120 yr) boreal mixedwood fo...

Background. Risk factors associated with renal dysfunction in patients on tenofovir remain unknown and optimal monitoring is unclear. We investigated whether a urine protein-osmolality ratio would be a useful screening parameter. Methods. This retrospective, single-center study of HIV-positive subjects investigated the relationship between three surrogates of renal function (eGFR, protein-osmol...

As is generally known, asbestos is physico chemically and economically suitable for building materials. However, respirable fine fibers of as bestos have been confirmed to cause asbestosis, bronchial cancer and pleural and peritoneal meso thelioma. As alternatives of asbestos, man-made mineral fibers such as glass fibers, ceramic fibers and others have been developed, but how they affect a pers...

Outcome of patients (pts) w/ stage I node neg HER2+ treated wkly paclitaxel x 12 doses and trastuzumab 1yr is excellent (10yr RFS 96%). Therefore, trials to de-escalate chemo use targeted therapy alone are underway. Zanidatamab a novel, humanized, bispecific, immunoglobulin G isotype 1-like, monoclonal antibody directed against the juxtamembrane extracellular domain (ECD4) dimerization (ECD2) H...