Drosophila APC has a role in maintaining adherens junctions, and also helps to tether mitotic spindles to the cortex and to orient them in the epithelial plane. In mammalian cells, APC has been implicated in cell migration. APC also helps safeguard the fidelity of chromosome segregation in mitotic cells. Loss of APC’s various functions at the cell periphery may contribute to tumour progression....

Humans and monkeys have access to an accurate representation of visual space despite a constantly moving eye. One mechanism by which the brain accomplishes this is by remapping visual receptive fields around the time of a saccade. In this process a neuron can be excited by a probe stimulus in the current receptive field, and also simultaneously by a probe stimulus in the location that will be b...

We review recommendations for sequencing instruction in receptive and expressive language objectives in early and intensive behavioral intervention (EIBI) programs. Several books recommend completing receptive protocols before introducing corresponding expressive protocols. However, this recommendation has little empirical support, and some evidence exists that the reverse sequence may be more ...

When a line extends beyond the width of an aperture, its direction of motion cannot be detected correctly. Only the component of motion perpendicular to the line is detectable (aperture problem). Early visual areas face the same aperture problem because receptive field sizes are relatively small. The susceptibility of early visual areas to the aperture problem opens an opportunity to measure th...

Die ISO27001:2005 als Informationssicherheitsmanagementsystem (ISMS) etabliert sich zunehmend als der Sicherheitsstandard in Unternehmen. Die Grundidee des ISMS basiert auf einem Management der Informationssicherheit welches ausgerichtet ist auf dem Management der Unternehmensrisiken und einen direkten Bezug zum Firmenumsatz herstellt. Bis September 2009 wurden weltweit mehr als 5822 1 zertifiz...

The previously monotypic genus Pseudorhopalia Wilcox & Papavero, 1971 is here revised, with description of a new species, Pseudorhopalia manauara, sp. n. The type-species, P. mirandai (d'Andretta & Carrera, 1951), is only found in northeastern Brazil, in the semiarid Caatinga biome. On the other hand, the new species is found in the humid Brazilian Amazonia, within dense ombrophilous forest and...

New Zealand contains 13 of the 69 species of Crotonia described globally and is the only place where all three genera of the Crotoniinae-Crotonia, Austronothrus and Holonothrus-have been recorded. Due to the pioneering work of Hammer (1966) and Luxton (1982) it also has the highest number of distribution records of Crotonia spp. anywhere. In the present study I build upon previous work to re-ex...

BACKGROUND Universal newborn hearing screening was implemented worldwide largely on modeled, not measured, long-term benefits. Comparative quantification of population benefits would justify its high cost. METHODS Natural experiment comparing 3 population approaches to detecting bilateral congenital hearing loss (>25 dB, better ear) in Australian states with similar demographics and services:...