نتایج جستجو برای: 213bi
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Over the past decade, there has been progressively stronger interest in the use of a-particle emitters for radioimmunotherapy (1–6). With proper localization of the labeled antibody, the high linear energy transfer of a-particles provides a correspondingly high probability of mitotic cell kill when compared with an equivalent number of cellular traversals by lower linear energy transfer b-parti...
Over the past decade, there has been progressively stronger interest in the use of a-particle emitters for radioimmunotherapy (1–6). With proper localization of the labeled antibody, the high linear energy transfer of a-particles provides a correspondingly high probability of mitotic cell kill when compared with an equivalent number of cellular traversals by lower linear energy transfer b-parti...
Brain metastases develop frequently in patients with breast cancer, and present a pressing therapeutic challenge. Expression of vascular cell adhesion molecule 1 (VCAM-1) is upregulated on brain endothelial cells during the early stages of metastasis and provides a target for the detection and treatment of early brain metastases. The aim of this study was to use a model of early brain metastasi...
BACKGROUND Alpha-particle emitting isotopes are effective novel tools in cancer therapy, but targeted delivery into tumors is a prerequisite of their application to avoid toxic side effects. Peritoneal carcinomatosis is a widespread dissemination of tumors throughout the peritoneal cavity. As peritoneal carcinomatosis is fatal in most cases, novel therapies are needed. F3 is a tumor homing pept...
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